COMBINED THERAPY FOR CANCER OF ANAL-CANAL - PRELIMINARY REPORT
COMBINED THERAPY FOR CANCER OF ANAL-CANAL - PRELIMINARY REPORT
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DOI：
10.1007/bf02586980
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发表时间：
1974-01-01
影响因子：
3.9
通讯作者：
CONSIDINE, B
中科院分区：
文献类型：
--
作者：
NIGRO, ND;VAITKEVICIUS, VK;CONSIDINE, B
与直肠腺癌相比，肛门癌并不常见。[2]根据Morson的研究，每28例直肠腺癌中就有1例鳞状细胞癌，发病率约为。'4.5%.因此，肛门癌的个人经验有限。幸运的是，最近的一些集体审查提供了治疗指南。手术已经在很大程度上取代了放射治疗作为肛门癌的主要治疗方式，特别是当有治愈的机会时。局部切除通常用于肛门边缘的癌症，而直肠切除术是肛管癌的首选治疗方法。肛缘癌的手术治疗效果良好，因为病变通常分化良好，但肛管癌的情况并非如此。这些病变与齿状线关系密切，是具有快速生长特征的肿瘤。它们是高度间变性的鳞状细胞癌，具有各种细胞类型，有时用术语描述，如”过渡性"、”基底细胞样”或”泄殖腔原性“。“这些tunaors通常预后不良。一
IN COMPARISON with adenocarcinoma of the rectum, anal cancer is uncommon. 2 According to Morson, a one squamous-cell cancer is seen for every 28 rectal adenocarcinomas, an incidence of about.'4.5 per cent. As a consequence, individual experience with anal cancer is limited. Fortunately, several recent collective reviews provide guidelines for treatment. 4, s Surgery has largely supplanted radiation therapy as the primary treatment modality for anal cancer, especially when there is a chance for cure. Local excision is usually done for cancer of the anal margin, while resection of the rectum is the preferred treatment for cancer of the anal canal. Resuhs of surgical treatment o~ cancer of the anal margin are good, since the lesions are usually well differentiated, but this is not the case with cancer of the anal canal. These lesions, which lie in close relationship to the dentate line, are neoplasms with rapid growth characteristics. They are highly anaplastic squamous cancers with various cell types sometimes described in terms such as" transitional,"" basaloid," or" cloacogenic." These tunaors generally have a poor prognosis. a