5' AND 3' TERMINAL NUCLEOTIDE-SEQUENCES OF THE RNA GENOME SEGMENTS OF INFLUENZA-VIRUS
5' AND 3' TERMINAL NUCLEOTIDE-SEQUENCES OF THE RNA GENOME SEGMENTS OF INFLUENZA-VIRUS
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DOI：
10.1093/nar/6.12.3745
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发表时间：
1979-01-01
影响因子：
14.9
通讯作者：
ROBERTSON, JS
中科院分区：
文献类型：
--
作者：
ROBERTSON, JS
对禽流感病毒禽瘟病毒基因组RNA片段的5′端和3′端进行了广泛的核苷酸序列分析，证实在每个片段的5′端和3′端都存在一个共同序列。在每个单独片段的末端之间存在互补序列，其在基因组的转录和复制的控制中可能是重要的。此外，还沿着指出了禽瘟病毒RNA翻译起始的可能位点以及病毒多肽的相应NH 2-末端氨基酸序列。
Extensive nucleotide sequence analysis of the 5′ and the 3′ termini of the RNA segments of the genome of fowl plague virus, an vian strain of influenza virus, confirms the presence of a common quence at the 5′ terminus of each segment and a common sequence at ne 3′ terminus of each segment. Between the ends of each individual egment there is a complementary sequence which may be important in the control of transcription and replication of the genome. In addition, the probable sites of initiation of translation of fowl plague virus RNA are indicated along with the corresponding NH2-terminal amino acid sequences of the virus polypeptides.