Cardiac autonomic balance versus cardiac regulatory capacity
Cardiac autonomic balance versus cardiac regulatory capacity
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DOI:
10.1111/j.1469-8986.2008.00652.x
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发表时间:
2008-07-01
期刊:
影响因子:
3.7
通讯作者:
Cacioppo, John T.
中科院分区:
文献类型:
--
作者:
Berntson, Gary G.;Norman, Greg J.;Cacioppo, John T.
The concept of autonomic balance views autonomic states along a bipolar continuum from sympathetic (S) to parasympathetic (P) dominance, whereas regulatory capacity models emphasize overall autonomic flexibility as a marker of the capacity for regulation. These two concepts were evaluated for their utility in characterizing patterns of autonomic control. Measures of P (high frequency heart rate variability, HF) and S (preejection period, PEP) cardiac control were obtained. A measure of cardiac autonomic balance (CAB) was derived as the difference in the normalized P index minus the S index, and a measure of cardiac autonomic regulation (CAR) was derived as the normalized P index plus the S index. Results reveal that CAR, but not CAB, was a significant predictor of the prior occurrence of a myocardial infarction, net of demographic and other variables, whereas CAB, but not CAR, was a significant predictor of concurrent diabetes.