Association of metabolic syndrome with morbidity and mortality in emergency general surgery
Association of metabolic syndrome with morbidity and mortality in emergency general surgery
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DOI：
10.1016/j.amjsurg.2019.12.021
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发表时间：
2020-08-01
影响因子：
3
通讯作者：
Merchant, Aziz M.
中科院分区：
文献类型：
--
作者：
Elsamna, Samer;Elkattawy, Omar;Merchant, Aziz M.
背景：代谢综合征（MetS）是由许多合并症定义的。我们试图评估MetS对7种主要急诊普通外科（EGS）手术（占EGS手术的80%）、死亡率、并发症和费用的影响。方法：从2005年至2017年的ACS-NSQIP数据库中获取数据。使用当前手术术语（CPT）代码识别病例。患有肥胖症、糖尿病和高血压的患者被定义为患有MetS。MetS和非MetS队列的倾向评分匹配，结果进行比较，并进行多变量logistic回归评估，以获得比值比（OR）。结果：在752,023例病例中，确定了41,788例（5.6%）MetS病例。显著结局包括浅表感染（OR：1.51）、肺部并发症（OR：1.17）、肾脏并发症（OR：1.82）、累积发病率（OR：1.22）和再入院（OR：1.41）。结论：对于接受这些手术的患者，MetS增加了合并症和再入院的风险。MetS仅对阑尾切除术的死亡率有显著影响。(c)2019爱思唯尔公司All rights reserved.
Background: Metabolic syndrome (MetS) is defined by numerous comorbidities. We sought to assess MetS's effect on the 7 main emergency general surgery (EGS) procedures that constitute 80% of EGS procedures, mortalities, complications, and costs. Methods: Data were acquired from the ACS-NSQIP database from 2005 to 2017. Current procedural terminology (CPT) codes were utilized to identify cases. Patients with obesity, diabetes, and hypertension were defined as having MetS. MetS and non-MetS cohorts were propensity score matched, compared by outcomes, and assessed with multivariate logistic regression to attain odds ratios (OR). Results: Of 752,023 cases, 41,788 (5.6%) MetS cases were identified. Significant outcomes included superficial infection (OR: 1.51), pulmonary complications (OR: 1.17), renal complications (OR: 1.82), cumulative morbidity (OR: 1.22), and hospital readmission (OR: 1.41). Conclusions: For patients undergoing these procedures, MetS increased risk for comorbidities and hospital readmission. MetS had a significant impact on mortality only for appendectomy. (c) 2019 Elsevier Inc. All rights reserved.