A +TIP for a smooth trip.
A +TIP for a smooth trip.
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旅途顺利的小贴士。
DOI：
10.1083/jcb.200511081
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发表时间：
2006
期刊：
影响因子：
--
通讯作者：
Xiang,Xin
中科院分区：
文献类型：
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作者：
Xiang,Xin
Is there a cellular mechanism for preventing a depolymerizing microtubule track from “slipping out from under” its cargo? A recent study in budding yeast indicates that when a chromosome is transported to the minus end of a spindle microtubule, its kinetochore-bound microtubule plus end–tracking protein (+TIP) Stu2 may move to the plus end to promote rescue; i.e., to switch the depolymerizing end to a polymerizing end. The possibility that other +TIPs may play a similar role in sustaining a microtubule track during vesicular transport deserves investigation.
