Republished viewpoint: Diabetes-induced osteoarthritis: from a new paradigm to a new phenotype

Republished viewpoint: Diabetes-induced osteoarthritis: from a new paradigm to a new phenotype
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DOI:
10.1136/pgmj.2010.146399rep
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发表时间:
2012-04-01
影响因子:
5.1
通讯作者:
Berenbaum, Francis
Berenbaum, Francis
中科院分区:
医学4区
文献类型:
--
作者:
Berenbaum, Francis

文献摘要

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一些流行病学和实验数据支持这样的假设:糖尿病可能是骨关节炎 (OA) 的独立危险因素,至少在某些患者中如此,从而提出了糖尿病诱发 OA 表型的概念。如果得到证实,这种新范式将对预防 QA 的启动和进展产生巨大影响。
Several epidemiological and experimental data support the hypothesis that diabetes could be an independent risk factor for osteoarthritis (OA), at least in some patients, leading to the concept of a diabetes-induced OA phenotype. If confirmed, this new paradigm will have a dramatic impact on prevention of QA intiation and progression.