Certain organochlorine and organobromine contaminants in Swedish human milk in perspective of past 20-30 years
Certain organochlorine and organobromine contaminants in Swedish human milk in perspective of past 20-30 years
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DOI：
10.1016/s0045-6535(99)00360-4
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发表时间：
2000-05-01
期刊：
影响因子：
8.8
通讯作者：
Meironyté, D
中科院分区：
文献类型：
--
作者：
Norén, K;Meironyté, D
对生活在斯德哥尔摩地区的妇女母乳中有机氯化合物的调查始于1967年。本研究总结了截至1997年不同时期母乳中多氯联苯（PCBs）、萘（PCNs）、二苯并二恶英（PCDDs）、二苯并呋喃（PCDFs）、多溴联苯醚（PBDEs）和杀虫剂（DDT、DDE、六氯苯、狄氏剂）以及PCBs和DDE的甲磺酰基代谢物的调查结果。在20-30年间，母乳中有机氯化合物的含量有不同程度的下降。在4-17年的时间范围内，浓度下降到原来的一半。与有机氯化合物相反，多溴二苯醚的浓度在1972-1997年期间有所增加，表明其浓度在5年内翻了一番。这些水平反映了环境污染和人口背景水平。多溴联苯醚的积累和持续增加要求立即采取措施，制止环境污染和人类接触多溴联苯醚。(C)2000爱思唯尔科技有限公司版权所有。
The investigations of organochlorine compounds in breast milk from women living in the Stockholm region started in 1967. The present study summarises the investigations of polychlorinated biphenyls (PCBs), naphthalenes (PCNs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), polybrominated diphenyl ethers (PBDEs) and pesticides (DDT, DDE, hexachlorobenzene, dieldrin) as well as methylsulfonyl metabolites of PCBs and DDE in human milk sampled during different periods up to 1997. During the course of 20-30 yr the levels of organochlorine compounds in human milk have decreased to various extent. A decrease to the half of the original concentration was attained in the range of 4-17 yr periods. On the contrary to the organochlorine compounds, the concentrations of PBDEs have increased during the period 1972-1997, indicating a doubling of the levels by 5 yr. The levels reflect the environmental contamination and background levels in the population. The accumulation and ongoing increase in the levels of PBDEs calls for immediate measures to stop the environmental pollution and human exposure to PBDEs. (C) 2000 Elsevier Science Ltd. All rights reserved.