Glucose, insulin, and the carotid body chemoreceptors in humans.

Glucose, insulin, and the carotid body chemoreceptors in humans.
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人类的葡萄糖、胰岛素和颈动脉体化学感受器。

DOI:
10.1152/physiolgenomics.00032.2018
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发表时间:
2018
影响因子:
4.6
通讯作者:
Limberg,JacquelineK
Limberg,JacquelineK
中科院分区:
生物学3区
文献类型:
--
作者:
Limberg,JacquelineK

文献摘要

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颈动脉体化学感受器主要因其氧传感能力而闻名,最近主要通过动物模型的工作,在许多代谢状况的病理生理学中有牵连。在这篇简短的综述中介绍的研究重点介绍了2010年至2017年期间在马约诊所对健康人群进行的转化工作,并讨论了未来在疾病人群中开展工作的关键领域。
Known primarily for its oxygen-sensing capabilities, the carotid body chemoreceptors have recently been implicated, primarily by work in animal models, in the pathophysiology of a number of metabolic conditions. The research presented in this brief review highlights translational work conducted at the Mayo Clinic between 2010 and 2017 in healthy humans and discusses key areas for future work in disease populations.