Prevalence of memory loss complaints and other symptoms associated with the menopause transition: a community survey.
Prevalence of memory loss complaints and other symptoms associated with the menopause transition: a community survey.
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DOI：
10.1016/s1550-8579(05)80055-5
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发表时间：
2005-12-01
期刊：
影响因子：
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通讯作者：
Zhivotovskaya, Emiliya
中科院分区：
文献类型：
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作者：
Devi, Gayatri;Hahn, Katherine;Zhivotovskaya, Emiliya
背景：越来越多的人注意到，记忆丧失是绝经过渡期症状的一部分。研究评估这种投诉在这一人群中产生了不同的result.OBJECTIVE：本研究的目的是确定是否投诉记忆丧失是一个组成部分的更年期过渡和一部分的更年期症状复杂的人口中的妇女不选择更年期symptoms.METHODS：教师成员长岛，纽约，学区被要求参加调查更年期症状。使用卡方（2）统计分析人口统计学数据。存在或不存在的记忆投诉，潮热/盗汗，阴道干燥，抑郁症，性欲下降，尿失禁进行了分析，作为二分变量的logistic回归分析后，调整人口差异。结果：百分之七十二（375/521）的教职员工在学区有资格，其中，217（58%）完成了调查。在排除了孕妇、子宫切除术或其他非绝经原因的闭经患者以及年龄60岁的患者后，151名妇女被纳入分析。其中103例（68%）处于自然绝经或围绝经期，48例（32%）月经周期无变化（对照组）。绝经期妇女明显比对照组妇女年长（平均[SD] 51.2 [5.0]岁vs 39.6 [7.2]岁; P < 0.001），并且她们比对照组妇女更可能是白色（P < 0.001）。有月经的女性抱怨失忆的可能性要高出几倍（比值比[OR]，3.2; 95% CI，1.2-8.8; P < 0.02），潮热/盗汗在调整了年龄和种族差异后，与对照组相比，女性的性欲下降（OR，4.3; 95% CI，1.4-13.3; P < 0.01）和性欲下降（OR，4.5; 95% CI，1.3-15.7; P < 0.02）。抑郁症、阴道干燥或失禁的患病率没有显着差异。结论：在我们的探索性调查中，记忆力丧失的投诉是更年期过渡症状综合征的一部分，潮热和性欲下降也是如此。对有这些症状的妇女进行纵向随访可能有助于了解妇女的更年期过渡。
BACKGROUND: Complaints of memory loss are increasingly noted as part of the constellation of symptoms experienced in the menopause transition. Studies evaluating such complaints in this population have yielded varying results.OBJECTIVE: The aim of this study was to determine if complaints of memory loss are a component of the menopause transition and a part of the menopausal symptom complex in a population of women not selected for menopausal symptoms.METHODS: Faculty members of a Long Island, New York, school district were asked to participate ina survey of menopausal symptoms. Demographic data were analyzed using chi(2) statistics. The presence or absence of memory complaints, hot flashes/night sweats, vaginal dryness, depression, reduced libido, and incontinence were analyzed as dichotomous variables in a logistic regression analysis after adjusting for demographic differences.RESULTS: Seventy-two percent (375/521) of the faculty members in the school district were eligible;of these, 217 (58%) completed the survey. After excluding pregnant women, those with hysterectomies or other nonmenopausal causes of amenorrhea, and those aged 60 years, 151 women were included in the analysis. Of these, 103 (68%) were experiencing natural menopause or perimenopause and 48 (32%) had no changes in menstrual cycle (the comparison group). The menopausal women were significantly older than the women in the comparison group (mean [SD] 51.2 [5.0] years vs 39.6 [7.2] years; P < 0.001), and they were more likely to be white than the women in the comparison group (P < 0.001). Menopausal women were several-fold more likely to complain of memory loss (odds ratio [OR], 3.2; 95% CI, 1.2-8.8; P < 0.02), hot flashes/night sweats (OR, 4.3; 95% CI, 1.4-13.3; P < 0.01), and reduced libido (OR, 4.5; 95% CI, 1.3-15.7; P < 0.02) than were women in the comparison group, after adjusting for differences in age and race. There were no significant differences in the prevalence of depression, vaginal dryness, or incontinence.CONCLUSIONS: In our exploratory survey, complaints of memory loss were a part of the symptom complex of the menopause transition, as were hot flashes and reduced libido. Longitudinal followup of women with these symptoms may be helpful in understanding the menopause transition in women.