Cranial Magnetic Resonance Imaging in Elderly American Indians: Design, Methods, and Implementation of the Cerebrovascular Disease and Its Consequences in American Indians Study
Cranial Magnetic Resonance Imaging in Elderly American Indians: Design, Methods, and Implementation of the Cerebrovascular Disease and Its Consequences in American Indians Study
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DOI：
10.1159/000443277
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发表时间：
2016-01-01
影响因子：
5.7
通讯作者：
Buchwald, Dedra
中科院分区：
文献类型：
--
作者：
Suchy-Dicey, Astrid M.;Shibata, Dean;Buchwald, Dedra
美国印第安人脑血管疾病及其后果（CDCAI）研究招募了一个20年的，纵向的，以人口为基础的美国印第安人队列的幸存成员，重点是心血管疾病，其危险因素及其后果。CDCAI研究的目的是描述颅脑MRI上确定的血管性脑损伤的负担、风险因素和表现。CDCAI研究调查人员招募了1,033名年龄在60岁及以上的参与者，他们来自北方平原、南方平原和美国西南部的11个美洲印第安社区和部落。除了根据标准化方案进行头颅MRI外，参与者还接受了广泛的医学访谈，临床检查，神经认知测试，身体功能评估，心电图，并提供血液和尿液标本。参与者还自我管理问卷，包括人口统计学，生活质量和病史。本报告描述了这项研究和数据收集的设计、实施和一些独特的挑战。(C)2016 S. Karger AG，巴塞尔
The Cerebrovascular Disease and its Consequences in American Indians (CDCAI) Study recruited surviving members of a 20-year, longitudinal, population-based cohort of American Indians focused on cardiovascular disease, its risk factors, and its consequences. The goal of the CDCAI Study is to characterize the burden, risk factors, and manifestations of vascular brain injury identified on cranial MRI. The CDCAI Study investigators enrolled 1,033 participants aged 60 and older from 11 American Indian communities and tribes in the Northern Plains, Southern Plains, and Southwestern United States. In addition to cranial MRI performed according to standardized protocols, participants underwent extensive medical interview, clinical examination, neurocognitive testing, physical function evaluation, electrocardiogram, and provided blood and urine specimens. Participants also self-administered questionnaires covering demographics, quality of life, and medical history. This report describes the design, implementation, and some of the unique challenges of this study and data collection. (C) 2016 S. Karger AG, Basel