Predicting N2pc from anticipatory HbO activity during sustained visuospatial attention: A concurrent fNIRS-ERP study
Predicting N2pc from anticipatory HbO activity during sustained visuospatial attention: A concurrent fNIRS-ERP study
复制标题
根据持续视觉空间注意力期间的预期 HbO 活动预测 N2pc：一项并行的 fNIRS-ERP 研究
DOI：
10.1016/j.neuroimage.2015.03.044
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发表时间：
2015-06-01
期刊：
影响因子：
5.7
通讯作者：
Song, Yan
中科院分区：
文献类型：
--
作者：
Huang, Jing;Wang, Fang;Song, Yan
了解注意力控制的特性以及支持它们的神经机制长期以来一直引起研究小组的密切关注。然而，尚未证明自上而下的预期血流动力学激活如何影响目标和干扰物的后续注意力处理。在这里，通过同时进行 fNIRS-ERP 记录，我们通过检查 HbO 如何影响随后假设反映注意力选择的 ERP N2pc 组件，探讨了基于预期氧合血红蛋白 (HbO) 的大脑活动对注意力控制的潜在贡献。我们发现，预期目标会导致即将到来的目标对侧视觉皮层准备性 HbO 反应大幅增加，这与随后目标诱发的 N2pc 幅度呈正相关。此外，对竞争性干扰物存在的预期会导致干扰物对侧视觉皮层中产生大量且长时间的准备性 HbO 信号，表明显着的干扰物可能会被准备性自上而下的注意力控制所主动抑制。然而，在随后的视觉搜索中，预抑制的干扰物仍然吸引了部分注意力，如 N2pc 振幅的降低所揭示的，并且对 N2pc 的这种干扰效果与预期干扰物对侧的准备性 HbO 增强呈负相关。总体而言，通过 fNIRS 测量的视觉皮层的预期血流动力学活动，可以提前预测每个人对目标的注意力转移以及对 ERP 测量的干扰物的抵抗力。 (C) 2015 Elsevier Inc. 保留所有权利。
Understanding the properties of attentional control, along with the neural mechanisms subserving them, has long invited intense scrutiny in research groups. However, it has not been demonstrated how the top-down anticipatory hemodynamic activation influences the subsequent attentional processing of targets and distractors. Here, with concurrent fNIRS-ERP recording, we explored the potential contribution of anticipatory oxygenated hemoglobin (HbO) based brain activity to attentional control by examining how HbO influences the subsequent ERP N2pc components assumed to reflect attentional selection. We found that expecting a target led to a larger increase of preparatory HbO response over the visual cortex contralateral to the upcoming target, which was positively correlated with the subsequent target-evoked N2pc amplitude. Further, anticipation concerning the presence of a competing distractor resulted in large and prolonged preparatory HbO signals in the visual cortex contralateral to the distractor, indicating that the salient distractor might be actively suppressed by preparatory top-down attentional control. However, the pre-suppressed distractor still captured part of the attention in the subsequent visual search as revealed by a decrease in the N2pc amplitude, and such a distraction effect on N2pc was negatively correlated with preparatory HbO enhancement contralateral to the anticipated distractor. Overall, each individuals attentional shift to the target and resistance to the distractor measured by ERP is predictable in advance via anticipatory hemodynamic activity in the visual cortex measured by fNIRS. (C) 2015 Elsevier Inc. All rights reserved.