NEUTRAL AMINO-ACIDS IN BRAIN - CHANGES IN RESPONSE TO FOOD INGESTION
NEUTRAL AMINO-ACIDS IN BRAIN - CHANGES IN RESPONSE TO FOOD INGESTION
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DOI：
10.1111/j.1471-4159.1978.tb10489.x
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发表时间：
1978-01-01
影响因子：
4.7
通讯作者：
FALLER, DV
中科院分区：
文献类型：
--
作者：
FERNSTROM, JD;FALLER, DV
The brain levels of each of the aromatic and branched-chain amino acids change 2 h after fasting rats begin to consume either a carbohydrate-fat diet or a similar diet containing 18% or 40% protein. Carbohydrate-fat ingestion elevates the concentrations of each of the aromatic amino acids in brain, while substantially depressing those of the branched-chain amino acids. The inclusion of protein in this diet suppresses the increases in brain aromatic amino acids and attenuates the decreases in the branched-chain amino acids. The changes in the brain level of each neutral amino acid following the ingestion of any of these diets correlate extremely well with the effects of the diet on the serum neutral amino acid pattern, specifically on the serum concentration ratio of each neutral amino acid to the sum of the other neutral amino acids. The diet-induced changes in the brain level of each of the amino acids also correlate surprisingly well with the calculated rate of brain influx for each amino acid.
