Determinants of normal retinal nerve fiber layer thickness measured by stratus OCT
Determinants of normal retinal nerve fiber layer thickness measured by stratus OCT
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DOI：
10.1016/j.ophtha.2006.08.046
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发表时间：
2007-06-01
期刊：
影响因子：
13.7
通讯作者：
Tielsch, James
中科院分区：
文献类型：
--
作者：
Budenz, Donald L.;Anderson, Douglas R.;Tielsch, James
目的：确定年龄、视盘面积、种族、眼睛、性别和眼轴长度对正常人眼视网膜神经纤维层（RNFL）的影响（通过Stratus OCT测量）设计：横断面观察研究。参与者：328名18至85岁的正常受试者。方法：随机选择每例受试者的一只眼，使用Stratus OCT进行视乳头周围快速RNFL扫描，以视盘为中心，标称直径为3.46 mm。年龄，种族，性别，眼睛，眼轴长度和视盘面积对perpapillary RNFL thickness.Results的影响的线性回归分析：整个人群的平均RNFL厚度为100.1 μ m（标准差，11.6）。较薄的RNFL测量值与年龄相关（P
Purpose: To determine the effects of age, optic disc area, ethnicity, eye, gender, and axial length on the retinal nerve fiber layer (RNFL) in the normal human eye as measured by Stratus OCT (optical coherence tomography).Design: Cross-sectional observational study.Participants: Three hundred twenty-eight normal subjects 18 to 85 years old.Methods: Peripapillary Fast RNFL scans performed by Stratus OCT with a nominal diameter of 3.46 mm centered on the optic disc were performed on one randomly selected eye of each subject.Main Outcome Measures: Linear regression analysis of the effects of age, ethnicity, gender, eye, axial length, and optic disc area on peripapillary RNFL thickness.Results: The mean RNFL thickness for the entire population was 100.1 mu m (standard deviation, 11.6). Thinner RNFL measurements were associated with older age (P