Influence of atrial fibrillation on the morbido-mortality of patients on hemodialysis

Influence of atrial fibrillation on the morbido-mortality of patients on hemodialysis
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DOI:
10.1067/mhj.2000.111111
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发表时间:
2000-12-01
影响因子:
4.8
通讯作者:
Perez, V
Perez, V
中科院分区:
医学2区
文献类型:
--
作者:
Vázquez, E;Sánchez-Perales, C;Perez, V

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背景 心房颤动 (AF) 对血液透析患者病死率的影响尚未得到充分探讨。本研究的目的是确定血液透析患者房颤的患病率,并评估其对血栓栓塞现象(TEP)发生的影响。方法对我们血液透析项目中的 190 名患者房颤发生率进行评估,并对患者进行为期 1 年的随访。将相关的人口统计学和生化参数输入单变量和多变量统计分析中,以评估与总体死亡率和 TEP(如脑血管意外、短暂性缺血性意外或外周栓塞)的关联。结果 13.6% 的患者发现 AF;13.6% 的患者发现 AF。其中 9.4% 为永久性类型。在多变量分析中,只有年龄增加与心律失常的较高概率相关(比值比,1.10;95% 置信区间,1.03-1.17;P =.003)。在随访期间,23% 的 AF 患者死亡,而 6% 的窦性心律患者死亡(P
Background The consequences of atrial fibrillation (AF) on morbido-mortality of patients on hemodialysis have not been fully explored. The objective of this study was to determine the prevalence of AF in patients on hemodialysis and to evaluate its influence on the development of thromboembolic phenomena (TEP).Methods The incidence of AF in 190 patients in our hemodialysis program was assessed, and the patients were followed up for 1 year. Pertinent demographic and biochemical parameters were entered into univariate and multivariate statistical analyses to evaluate associations with overall mortality and TEP such as cerebrovascular accident, transitory ischemic accident, or peripheral embolism.Results In 13.6% of patients, AF was found; 9.4% of these were of the permanent type. In the multivariate analysis, only increased age was associated with a higher probability of having arrhythmia (odds ratio, 1.10; 95% confidence interval, 1.03-1.17; P =.003). During follow-vp, 23% of the patients with AF died compared with 6% of those in sinus rhythm (P