BRENDA, AMENDA and FRENDA: the enzyme information system in 2007.
BRENDA, AMENDA and FRENDA: the enzyme information system in 2007.
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Brenda，Amenda和Frenda：2007年的酶信息系统。
DOI：
10.1093/nar/gkl972
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发表时间：
2007-01
影响因子：
14.9
通讯作者：
Schomburg, Dietmar
中科院分区：
文献类型：
--
作者：
Barthelmes, Jens;Ebeling, Christian;Chang, Antje;Schomburg, Ida;Schomburg, Dietmar
BRENDA（BRaunschweig ENzyme DAtplant）酶信息系统（）是全球最大的公开酶信息系统。其内容的主要部分是从原始文献中手动提取的。它不限于特定的酶组，但包括所有确定的酶的信息，无论酶的来源。数据范围包括功能、结构、序列、定位、疾病相关、分离、酶和配体相关数据的稳定性信息。每个条目都链接到酶来源和参考文献。最近，数据存储库补充了文本挖掘数据在AMENDA（自动挖掘酶数据）和FRENDA（完整参考酶数据）。增加了基因组浏览器、膜蛋白预测和全文搜索功能。新实现的Web服务通过SOAP（简单对象访问协议）接口为程序员提供了对数据的即时访问。从2007年初开始，可以以文本文件的形式下载BRENDA数据。
The BRENDA (BRaunschweig ENzyme DAtabase) enzyme information system () is the largest publicly available enzyme information system worldwide. The major parts of its contents are manually extracted from primary literature. It is not restricted to specific groups of enzymes, but includes information on all identified enzymes irrespective of the enzyme's source. The range of data encompasses functional, structural, sequence, localisation, disease-related, isolation, stability information on enzyme and ligand-related data. Each single entry is linked to the enzyme source and to a literature reference. Recently the data repository was complemented by text-mining data in AMENDA (Automatic Mining of ENzyme DAta) and FRENDA (Full Reference ENzyme DAta). A genome browser, membrane protein prediction and full-text search capacities were added. The newly implemented web service provides instant access to the data for programmers via a SOAP (Simple Object Access Protocol) interface. The BRENDA data can be downloaded in the form of a text file from the beginning of 2007.