MOLECULAR STRUCTURE OF NUCLEIC ACIDS - A STRUCTURE FOR DEOXYRIBOSE NUCLEIC ACID
MOLECULAR STRUCTURE OF NUCLEIC ACIDS - A STRUCTURE FOR DEOXYRIBOSE NUCLEIC ACID
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DOI：
10.1038/171737a0
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发表时间：
1953-01-01
期刊：
影响因子：
64.8
通讯作者：
CRICK, FHC
中科院分区：
文献类型：
--
作者：
WATSON, JD;CRICK, FHC
脱氧核糖核酸（DNA）--生命的新转折1953年，脱氧核糖核酸（DNA）的结构被X射线晶体学确定，DNA具有两个包绕螺旋和成对的有机碱基。但更重要的是，它也为更深入地了解可能是最重要的生物过程开辟了道路。用沃森和克里克的话来说：“我们注意到，我们假设的特定配对立即暗示了遗传物质的可能复制机制。[弗朗西斯克里克的讣告：自然430，845-847（2004）;莫里斯威尔金斯的讣告：自然431，922（2004）]
DNA — a new twist on lifeThe determination in 1953 of the structure of deoxyribonucleic acid (DNA), with its two entwined helices and paired organic bases, was atour de forcein X-ray crystallography. But more significantly, it also opened the way for a deeper understanding of perhaps the most important biological process. In the words of Watson and Crick: "It has not escaped our notice that the specific pairing that we have postulated immediately suggests a possible copying mechanism for the genetic material." [Obituary of Francis Crick:Nature430, 845-847 (2004); obituary of Maurice Wilkins:Nature431, 922 (2004)]