Continued maturation of auditory brainstem function during adolescence: A longitudinal approach.
Continued maturation of auditory brainstem function during adolescence: A longitudinal approach.
复制标题
DOI：
10.1016/j.clinph.2015.01.026
复制
发表时间：
2015-12
期刊：
影响因子：
--
通讯作者：
Kraus N
中科院分区：
文献类型：
--
作者：
Krizman J;Tierney A;Fitzroy AB;Skoe E;Amar J;Kraus N
相当多的注意力已经投入到理解听觉系统的发展在生命的头几年，但相对较少的是了解成熟在青春期。此外，少数调查儿童后期听觉系统成熟的研究采用了横断面方法。为了更好地了解青少年的听觉发展，我们采用纵向设计来测量74名青少年在14至17岁的四个时间点的语音音节的皮层下编码。我们发现，在唤起音节的频谱表征、一次又一次的反应一致性和幅度包络的跟踪方面，出现了发展的减少，而在这个年龄范围内，诱发反应的时间似乎是稳定的。这些纵向数据进一步证明，皮层下听觉发育是一个长期的过程，贯穿生命的头二十年。具体来说，我们的数据表明，青春期代表了童年时期的增强反应和成年人的成熟反应之间的一个过渡点，尽管反应较小。到青春期结束时，听觉脑干还没有完全成熟，这表明在童年后期开始的听觉丰富可能会导致听觉脑干功能的增强，并改变发育特征。
Considerable attention has been devoted to understanding development of the auditory system during the first few years of life, yet comparatively little is known about maturation during adolescence. Moreover, the few studies investigating auditory system maturation in late childhood have employed a cross-sectional approach. To better understand auditory development in adolescence, we used a longitudinal design to measure the subcortical encoding of speech syllables in 74 adolescents at four time points from ages 14 through 17. We find a developmental decrease in the spectral representation of the evoking syllable, trial-by-trial response consistency, and tracking of the amplitude envelope, while timing of the evoked response appears to be stable over this age range. These longitudinal data provide further evidence that subcortical auditory development is a protracted process that continues throughout the first two decades of life. Specifically, our data suggest that adolescence represents a transitional point between the enhanced response during childhood and the mature, though smaller, response of adults. That the auditory brainstem has not fully matured by the end of adolescence suggests that auditory enrichment begun later in childhood could lead to enhancements in auditory brainstem function and alter developmental profiles.