Self-initiated actions result in suppressed auditory but amplified visual evoked components in healthy participants
Self-initiated actions result in suppressed auditory but amplified visual evoked components in healthy participants
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DOI：
10.1111/psyp.12605
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发表时间：
2016-05-01
期刊：
影响因子：
3.7
通讯作者：
Whitford, Thomas J.
中科院分区：
文献类型：
--
作者：
Mifsud, Nathan G.;Oestreich, Lena K. L.;Whitford, Thomas J.
自我抑制是指与外部世界变化产生的感觉相比，我们自己的运动引发的感觉通常不那么明显，并且引起的神经反应减弱。先前针对听觉模式的 ERP 研究提供了自我抑制的证据，这些研究发现，当听觉刺激是自我启动而不是外部启动时，健康参与者通常会表现出听觉 N1 成分减少。然而，研究视觉形态中自我抑制的文献很少，研究结果和实验方案混杂不一。进行了一项脑电图研究，以扩大我们对不同感觉方式的自我抑制的理解。健康参与者在按意愿按钮（自我启动）、随机间隔（外部启动、不可预测的开始）或视觉倒计时（外部启动、可预测的开始以匹配自我启动刺激的内在可预测性）之后经历听觉（音调）或视觉（模式反转）刺激，同时连续记录脑电图。与外部发起的音调相比，自身音调的 N1 幅度降低表明听觉领域发生了自我抑制。相比之下，视觉 N145 成分在自我与外部启动的模式逆转时被放大。外部引发的条件并没有因其可预测性而有所不同。这些发现强调了不同方式对自我发起刺激的感觉处理的差异，并可能对表面上与异常自我抑制相关的临床疾病产生影响。
Self-suppression refers to the phenomenon that sensations initiated by our own movements are typically less salient, and elicit an attenuated neural response, compared to sensations resulting from changes in the external world. Evidence for self-suppression is provided by previous ERP studies in the auditory modality, which have found that healthy participants typically exhibit a reduced auditory N1 component when auditory stimuli are self-initiated as opposed to externally initiated. However, the literature investigating self-suppression in the visual modality is sparse, with mixed findings and experimental protocols. An EEG study was conducted to expand our understanding of self-suppression across different sensory modalities. Healthy participants experienced either an auditory (tone) or visual (pattern-reversal) stimulus following a willed button press (self-initiated), a random interval (externally initiated, unpredictable onset), or a visual countdown (externally initiated, predictable onsetto match the intrinsic predictability of self-initiated stimuli), while EEG was continuously recorded. Reduced N1 amplitudes for self- versus externally initiated tones indicated that self-suppression occurred in the auditory domain. In contrast, the visual N145 component was amplified for self- versus externally initiated pattern reversals. Externally initiated conditions did not differ as a function of their predictability. These findings highlight a difference in sensory processing of self-initiated stimuli across modalities, and may have implications for clinical disorders that are ostensibly associated with abnormal self-suppression.