Diversity synthesis using the complimentary reactivity of rhodium(II)- and palladium(II)-catalyzed reactions.
Diversity synthesis using the complimentary reactivity of rhodium(II)- and palladium(II)-catalyzed reactions.
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利用铑 (II) 和钯 (II) 催化反应的互补反应性进行多样性合成。
DOI：
10.1021/jo060636u
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发表时间：
2006
期刊：
影响因子：
--
通讯作者：
Davies,HuwML
中科院分区：
文献类型：
--
作者：
Ni,Aiwu;France,JessicaE;Davies,HuwML
Rh(II)催化的芳基重氮乙酸酯在碘、三氟化钠、有机硼和有机锡烷官能团存在下的反应可以生成多种环丙烷或具有高立体选择性的C-−-H插入产物。Rh(II)催化的反应和随后的Pd(II)催化的Suzuki偶联的结合为多样性合成提供了一种新的策略。
Rhodium(II)-catalyzed reactions of aryldiazoacetates can be conducted in the presence of iodide, triflate, organoboron, and organostannane functionality, resulting in the formation of a variety of cyclopropanes or C−H insertion products with high stereoselectivity. The combination of the rhodium(II)-catalyzed reaction with a subsequent palladium(II)-catalyzed Suzuki coupling offers a novel strategy for diversity synthesis.