Cost of poor blood pressure control in the UK: 62 000 unnecessary deaths per year

Cost of poor blood pressure control in the UK: 62 000 unnecessary deaths per year
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DOI:
10.1038/sj.jhh.1001581
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发表时间:
2003-07-01
影响因子:
2.7
通讯作者:
MacGregor, GA
MacGregor, GA
中科院分区:
医学4区
文献类型:
--
作者:
He, FJ;MacGregor, GA

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高血压是心血管疾病最重要的危险因素。根据最近发表的前瞻性研究的荟萃分析中关于收缩压的信息,我们计算了在将所有高血压患者的收缩压控制在140毫米汞柱的情况下,中风和缺血性心脏病的减少。对于成年人来说,根据年龄的不同,中风的发病率将减少28%-44%,缺血性心脏病的发病率将减少20%-35%。在英国,这将每年防止约21 400人死于中风和41 400人死于缺血性心脏病。大约一半的中风或缺血性心脏病患者存活下来,这些人的存活率也会相应下降。这相当于减少了大约42800次中风和82800例缺血性心脏病,使英国每年总共减少了12.56万次事件。这将减少残疾,并为个人、其家庭和保健服务节省大量费用。许多国家的血压水平和对血压的控制与英国相似,因此,如果能够获得对高血压的同样控制,全球中风和缺血性心脏病的减少将是巨大的。
High blood pressure is the most important risk factor for cardiovascular disease. With the information on systolic blood pressure from the recently published meta-analysis of prospective studies, we calculated the reductions in stroke and ischaemic heart disease with control of all hypertensives to a systolic blood pressure of 140 mmHg. For adults there would be a reduction of 28-44% in stroke and 20-35% in ischaemic heart disease depending on age. In the UK, this would prevent approximately 21 400 stroke deaths and 41 400 ischaemic heart disease deaths each year. Around half of those who suffer a stroke or ischaemic heart disease survive, there would be a proportionate decrease in these people as well. These amount to approximately 42 800 strokes and 82 800 ischaemic heart diseases saved, making a total of 125 600 events saved a year in the UK. This would result in a reduction in disability and major cost savings both to individuals, their families and the Health Service. The blood pressure levels and control of blood pressure in many countries are similar to those in the UK, so the reductions in stroke and ischaemic heart disease worldwide, if the same control of high blood pressure could be obtained, would be immense.