The SARS outbreak in a general hospital in Tianjin, China - the case of super-spreader
The SARS outbreak in a general hospital in Tianjin, China - the case of super-spreader
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DOI：
10.1017/s095026880500556x
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发表时间：
2006-08-01
影响因子：
4.2
通讯作者：
Wang, P. P.
中科院分区：
文献类型：
--
作者：
Wang, Sh. X.;Li, Y. M.;Wang, P. P.
严重急性呼吸道综合症（SARS）是一种新出现的传染病，病死率高，对社会经济造成破坏性影响。在本报告中，我们总结了 2003 年 4 月至 5 月期间对天津一家医院爆发的 SARS 疫情进行的流行病学调查结果。我们收集了 111 例与此次疫情爆发相关的 SARS 疑似病例和疑似病例的流行病学和临床数据。对传播链和爆发集群进行了调查。此次疫情来源单一，有八个聚集性疫情。该院所有SARS病例均由一名患者直接传染，导致33人感染。患者年龄从16岁到82岁不等（平均年龄38(.)5岁）； 38(.)7% 是男性。 SARS 爆发的总体病死率为 11(.)7% (13/111)。自发现指示病例后，疫情持续了约 4 周。 SARS 是一种高度传染性的疾病，导致大量病例死亡；暴发。可由一名患者在相对较短的时间内产生。然而，严格的公共卫生措施似乎能有效打破疾病传播链。
Severe acute respiratory syndrome (SARS) is a newly emerged infectious disease with a high case-fatality rate and devastating socio-economic impact. In this report we summarized the results from an epidemiological investigation of a SARS outbreak in a hospital in Tianjin, between April and May 2003. We collected epidemiological and clinical data on 111 suspect and probable cases of SARS associated with the outbreak. Transmission chain and outbreak clusters were investigated. The outbreak was single sourced and had eight clusters. All SARS cases in the hospital were traced to a single patient who directly infected 33 people. The patients ranged from 16 to 82 years of age (mean age 38(.)5 years); 38(.)7% were men. The overall case fatality in the SARS outbreak was 11(.)7% (13/111). The outbreak lasted around 4 weeks after the index case was identified. SARS is a highly contagious condition associated with substantial case fatality; an outbreak. can result from one patient in a relatively short period. However, stringent public health measures seemed to be effective in breaking the disease transmission chain.