IMPAIRED RECOGNITION OF EMOTION IN FACIAL EXPRESSIONS FOLLOWING BILATERAL DAMAGE TO THE HUMAN AMYGDALA
IMPAIRED RECOGNITION OF EMOTION IN FACIAL EXPRESSIONS FOLLOWING BILATERAL DAMAGE TO THE HUMAN AMYGDALA
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DOI：
10.1038/372669a0
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发表时间：
1994-12-15
期刊：
影响因子：
64.8
通讯作者：
DAMASIO, A
中科院分区：
文献类型：
--
作者：
ADOLPHS, R;TRANEL, D;DAMASIO, A
对动物的研究表明，杏仁核接收高度加工的视觉输入（1，2），含有对面孔有选择性反应的神经元（3），它参与情绪（4，5）和社会行为（6）。虽然对癫痫患者的研究支持其在情绪中的作用（7），但人类杏仁核功能的确定受到选择性杏仁核病变患者罕见的阻碍（8）。在这里，在一位罕见患者的帮助下，我们报告的发现表明，人类杏仁核可能是不可或缺的：（1）识别面部表情中的恐惧;（2）识别单一面部表情中的多种情绪;但（3）不需要从面部识别个人身份。这些结果表明，仅限于杏仁核的损伤导致非常具体的识别障碍，从而限制了杏仁核参与情绪的广泛概念。
STUDIES in animals have shown that the amygdala receives highly processed visual input(1,2), contains neurons that respond selectively to faces(3), and that it participates in emotion(4,5) and social behaviour(6). Although studies in epileptic patients support its role in emotion(7), determination of the amygdala's function in humans has been hampered by the rarity of patients with selective amygdala lesions(8). Here, with the help of one such rare patient, we report findings that suggest the human amygdala may be indispensable to: (1) recognize fear in facial expressions; (2) recognize multiple emotions in a single facial expression; but (3) is not required to recognize personal identity from faces. These results suggest that damage restricted to the amygdala causes very specific recognition impairments, and thus constrains the broad notion that the amygdala is involved in emotion.