Racial/ethnic differences in age-related maculopathy. Third National Health and Nutrition Examination Survey.

Racial/ethnic differences in age-related maculopathy. Third National Health and Nutrition Examination Survey.
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DOI:
10.1016/s0161-6420(95)31012-3
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发表时间:
1995-03
期刊:
影响因子:
13.7
通讯作者:
R. Klein;Michael L. Rowland;Maureen I Harris
R. Klein;Michael L. Rowland;Maureen I Harris
中科院分区:
医学1区
文献类型:
--
作者:
R. Klein;Michael L. Rowland;Maureen I Harris

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目的:调查年龄相关性黄斑病变的患病率在三个种族/民族,非西班牙裔白人,非西班牙裔黑人,和墨西哥裔American.Methods:人40岁或以上谁参加了一个全国代表性的人口为基础的样本的第三次全国健康和营养检查调查进行了检查,从1988年至1991年。视网膜相关的黄斑病变的眼底照片,使用一个标准化的协议为样本的4007 persons.Results:任何年龄相关的黄斑病变的患病率在平民noninstitutionalized美国人口,包括那些40岁或以上的估计样本为9.2%。非西班牙裔白人(9.3%)的患病率高于非西班牙裔黑人(7.4%)和墨西哥裔美国人(7.1%)。在60岁之前,墨西哥裔美国人(比值比[OR],1.53; 95%置信区间[CI] 1.0-2.35)和非西班牙裔黑人(OR,1.59; 95% CI,0.86-2.95)比非西班牙裔白人有更大的机会患有任何黄斑病变;此后,墨西哥裔美国人(OR,0.63; 95%CI,0.44-0.90)和非西班牙裔黑人(OR,0.50; 95%CI,0.37-0.68)有一个较小的机会比非西班牙裔white.Conclusion:这些调查数据表明,年龄相关性黄斑病变是普遍存在于所有群体的研究。种族/族裔群体之间的差异因年龄和性别而异。
Purpose:To investigate the prevalence of age-related maculopathy in three racial/ethnic groups, non-Hispanic whites, non-Hispanic blacks, and Mexican Americans.Methods:People 40 years of age or older who participated in a nationally representative population-based sample of the Third National Health and Nutrition Examination Survey were examined from 1988 to 1991. Age-related maculopathy was determined by grading of fundus photographs using a standardized protocol for a sample of 4007 persons.Results:The prevalence of any age-related maculopathy in the civilian noninstitutionalized United States population including those 40 years of age or older was 9.2% as estimated from the sample. Prevalence was higher in non-Hispanic whites (9.3%) compared with non-Hispanic blacks (7.4%)and Mexican Americans (7.1%). Before 60 years of age, Mexican Americans (odds ratio [OR], 1.53; 95% confidence interval [CI] 1.0–2.35) and non-Hispanic blacks (OR,1.59; 95% CI, 0.86–2.95) had a greater chance of having any maculopathy than non-Hispanic whites; thereafter, Mexican Americans (OR, 0.63; 95% CI, 0.44–0.90) and non-Hispanic blacks (OR, 0.50; 95% CI, 0.37–0.68) had a lesser chance than non-Hispanic whites.Conclusion:These survey data indicate that age-related maculopathy is prevalent in all groups studied. Differences among the racial/ethnic groups vary by age and sex.