The burden of adult asthma in the United States: Evidence from the Medical Expenditure Panel Survey
The burden of adult asthma in the United States: Evidence from the Medical Expenditure Panel Survey
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DOI：
10.1016/j.jaci.2010.10.042
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发表时间：
2011-02-01
影响因子：
14.2
通讯作者：
Lin, Shao-Lee
中科院分区：
文献类型：
--
作者：
Sullivan, Patrick W.;Ghushchyan, Vahram H.;Lin, Shao-Lee
背景：重要的是要准确了解医疗支出和生产力损失的来源和程度，以了解美国哮喘负担的性质和范围。目的：目前的研究旨在提供美国成年人哮喘直接和与生产力相关的成本的最新全国代表性估计。方法：采用2003年和2005年的医疗支出小组调查来估计哮喘对成人（>= 18岁）医疗支出、使用、生产力和慢性合并症的影响。与生产率相关的结果变量包括就业、年收入、旷工天数、卧病天数和活动限制。进行多元回归，控制社会人口统计学和合并症。结果：在47033名成年人中，2003人报告患有哮喘。与没有哮喘的人相比，哮喘患者就业的可能性显著降低（优势比为0.78），每年多卧床1.4天，活动受限或无法工作的可能性显著增加。患有哮喘的成年人每年额外花费1,907美元（2008年美元），并且经历了更高的卫生保健使用和合并症。成人哮喘导致的全国医疗支出总额为180亿美元。患有哮喘的成年人（30%）比一般成年人（10%）更有可能被医疗补助覆盖。成人哮喘患者医疗支出的最大贡献者是处方药，其次是住院治疗和家庭保健。结论：在最近的国家数据中，成人哮喘与美国直接和间接成本的显著有害影响相关。[J] .中华过敏症杂志，2011;27:363-9。
Background: It is important to have an accurate picture of the sources and extent of medical expenditures and productivity loss to understand the nature and scope of the burden of asthma in the United States (US).Objective: The current study aims to provide recent nationally representative estimates of direct and productivity-related costs attributable to asthma in adults in the US.Methods: The 2003 and 2005 Medical Expenditure Panel Surveys were used to estimate the effect of asthma on medical expenditures, use, productivity, and chronic comorbidity among adults (>= 18 years). Productivity-related outcome variables included employment, annual wages, missed work days, days spent sick in bed, and activity limitations. Multivariate regression was conducted, controlling for sociodemographics and comorbidity.Results: Of 47,033 adults, 2,003 reported asthma. Compared with those without, subjects with asthma were significantly less likely to be employed (odds ratio, 0.78), spent 1.4 more days sick in bed annually, and were significantly more likely to have activity limitations or to be unable to work. Adults with asthma incurred an additional $1,907 (2008 US dollars) annually and experienced higher health care use and comorbidity. The total national medical expenditure attributable to adult asthma was $18 billion. Adults with asthma were more likely to be covered by Medicaid (30%) than the general adult population (10%). The largest contributors to medical expenditures for adults with asthma were prescription drugs, followed by inpatient hospitalizations and home health care.Conclusions: In recent national data adult asthma is associated with a significant deleterious effect on direct and indirect costs in the US. (J Allergy Clin Immunol 2011;127:363-9.)