Triterpenoid saponins from the root of Anemone tomentosa
Triterpenoid saponins from the root of Anemone tomentosa
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DOI：
10.1007/s11418-012-0649-8
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发表时间：
2013-01-01
影响因子：
3.3
通讯作者：
Tian, Xiang-rong
中科院分区：
文献类型：
--
作者：
Wang, Yi;Kang, Wei;Tian, Xiang-rong
从毛蕊海葵根中分离到3个新的三萜皂苷，毛蕊皂苷A(1)、B(2)和C(3)，以及4个已知的皂苷（4-7）。新化合物的结构经鉴定为：3- o - β -d- rbpyranosyl -(1 -> 3)- α -l-rhamnopyranosyl-(1 -> 2)-[β -d-glucopyranosyl-(1 -> 4)]- α -l-arabinopyranosyl hederagenin 28- o - α -l-rhamnopyranosyl-(1 -> 4)- β -d-glucopyranosyl-(1 -> 6)- β -d-glucopyranosyl-(1 -> 6)- β -d-glucopyranosyl (1)；3-O-beta-d-ribopyranosyl - (1 - > 3) -alpha-l-rhamnopyranosyl (1 - > 2) - [beta-d-glucopyranosyl - (1 - > 4)] -beta-d-xylopyranosyl hederagenin 28-O-alpha-l-rhamnopyranosyl - (1 - > 4) -beta-d-glucopyranosyl (1 - > 6) -beta-d-glucopyranoside(2)和3-O-beta-d-galactopyranosyl - (1 - > 3) -alpha-l-rhamnopyranosyl (1 - > 2) -beta-d-xylopyranosyl齐墩果酸28-O-alpha-l-rhamnopyranosyl - (1 - > 4) -beta-d-glucopyranosyl (1 - > 6) -beta-d-glucopyranoside(3)的基础上化学和光谱证据。在化合物3的低聚糖链中，d-半乳糖残基是罕见的结构特征，也是海葵三萜皂苷中少见的结构特征。
Three new triterpenoid saponins, tomentoside A (1), B (2) and C (3), along with four known saponins (4-7) were isolated from the root of Anemone tomentosa. The structures of the new compounds were elucidated as 3-O-beta-d-ribopyranosyl-(1 -> 3)-alpha-l-rhamnopyranosyl-(1 -> 2)-[beta-d-glucopyranosyl-(1 -> 4)]-alpha-l-arabinopyranosyl hederagenin 28-O-alpha-l-rhamnopyranosyl-(1 -> 4)-beta-d-glucopyranosyl-(1 -> 6)-beta-d-glucopyranoside (1), 3-O-beta-d-ribopyranosyl-(1 -> 3)-alpha-l-rhamnopyranosyl-(1 -> 2)-[beta-d-glucopyranosyl-(1 -> 4)]-beta-d-xylopyranosyl hederagenin 28-O-alpha-l-rhamnopyranosyl-(1 -> 4)-beta-d-glucopyranosyl-(1 -> 6)-beta-d-glucopyranoside (2) and 3-O-beta-d-galactopyranosyl-(1 -> 3)-alpha-l-rhamnopyranosyl-(1 -> 2)-beta-d-xylopyranosyl oleanolic acid 28-O-alpha-l-rhamnopyranosyl-(1 -> 4)-beta-d-glucopyranosyl-(1 -> 6)-beta-d-glucopyranoside (3) on the basis of chemical and spectral evidence. In the oligosaccharide chains of compound 3, the characteristic d-galactose residue is a rare structural feature and secondly encountered among triterpenoid saponins from Anemone.