Surrogate parameter for the baseline toxicity content of contaminated water: simulating the bioconcentration of mixtures of pollutants and counting molecules.
Surrogate parameter for the baseline toxicity content of contaminated water: simulating the bioconcentration of mixtures of pollutants and counting molecules.
复制标题
DOI：
10.1021/es00003a021
复制
发表时间：
1995-03
影响因子：
11.4
通讯作者：
H. Verhaar;F. Busser;J. Hermens
中科院分区：
文献类型：
--
作者：
H. Verhaar;F. Busser;J. Hermens
就急性水生毒性而言，所有环境污染物的很大一部分可归类为麻醉性化学品。一般认为，这种基线或嗜睡型毒性是通过同一种机制产生的。这些化学物质的影响与它们的（平衡）身体负荷直接相关。这意味着，水生样本的“总基线毒性含量”仅取决于这些化合物的累积身体负荷，并可将其作为水生生态系统风险评估的一个重要参数。本文描述了一种简单的程序，通过使用c18 -Empore圆盘模拟污染物混合物的生物体负荷，并随后通过蒸汽压渗透法以摩尔浓度为基础量化这种累积体负荷。这一程序满足了估算环境水样的总基线毒性含量的真正替代参数的要求，因为它不需要对个别化合物进行识别和量化，并且能够估算基线毒性对地表水和流出物的总体毒性的贡献。
A large part of all environmental pollutants can be classified as narcosis-type chemicals with regard to acute aquatic toxicity. This baseline, or narcosis-type, toxicity is generally assumed to be brought about through one and the same mechanism. The effects of these chemicals are directly related to their (equilibrium) body burden. This implies that the 'total baseline toxicity content' of an aquatic sample is dependent only on the cumulative body burden of these compounds and that this could be made into an important parameter in risk assessment for the aquatic ecosystem. A simple procedure to simulate the biotic body burden of a mixture of pollutants, by using C 18 -Empore disks and to subsequently quantify this cumulative body burden on the basis of molar concentrations by means of vapor pressure osmometry is described. This procedure fulfils the requirements of a true surrogate parameter for the estimation of the total baseline toxicity content of environmental water samples by obviating the need of identifying and quantifying individual compounds and by enabling an estimation of the contribution of baseline toxicity to the overall toxicity of surface waters and effluents.