A systematic review of intracranial chondrosarcoma and survival.

A systematic review of intracranial chondrosarcoma and survival.
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对颅内软骨肉瘤和生存的系统评价。

DOI:
10.1016/j.jocn.2009.05.003
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发表时间:
2009-12
影响因子:
2
通讯作者:
Parsa, Andrew T.
Parsa, Andrew T.
中科院分区:
医学4区
文献类型:
--
作者:
Bloch, Orin G.;Jian, Brian J.;Yang, Isaac;Han, Seunggu J.;Aranda, Derick;Ahn, Brian J.;Parsa, Andrew T.

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大多数关于软骨肉瘤患者生存率的数据仅限于在单个机构进行的病例研究和小系列研究。我们进行了一项系统的综述来研究所提出的预后因素与生存率之间的关系。每一项发表在英国文献上的研究都被回顾了。根据治疗方式、治疗史、组织学亚型和组织学分级对患者的死亡率进行分析。对560例颅骨软骨肉瘤患者进行分析。中位随访时间为60个月。所有患者5年死亡率为11.5%,中位生存期为24个月。与相应的患者相比,更高级别肿瘤或间充质亚型肿瘤患者或仅接受手术切除的患者5年死亡率明显更高。我们的系统评价结果为预测颅骨软骨肉瘤患者的生存提供了有用的数据。
Most data regarding survival in patients with chondrosarcoma are limited to case studies and small series performed at single institutions. A systematic review was performed to study the relationship between proposed prognostic factors and survival. Every study published in the English literature was reviewed. The mortality rates in these patients were analyzed according to modality of treatment, treatment history, histological subtype, and histological grade. A total of 560 patients with cranial chondrosarcoma were analyzed. Median follow-up time was 60 months. The 5-year mortality among all patients was 11.5% with median survival of 24 months. Mortality at 5 years was significantly greater for patients with tumors of higher grade or of the mesenchymal subtype, or had received surgical resection alone, when compared to their respective counterparts. The results of our systematic review provide useful data in predicting survival among cranial chondrosarcoma patients.
DOI: 10.3171/jns.1989.70.1.0013
发表时间: 1989-01-01
影响因子: 4.1
作者:
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