A polycation-chaperoned in-stem molecular beacon system
A polycation-chaperoned in-stem molecular beacon system
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DOI：
10.1039/c2cc16812j
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发表时间：
2012-01-01
影响因子：
4.9
通讯作者：
Maruyama, Atsushi
中科院分区：
文献类型：
--
作者：
Asanuma, Hiroyuki;Osawa, Takuya;Maruyama, Atsushi
在聚（L-赖氨酸）-接枝-葡聚糖的存在下，在干分子信标涉及三个在干区域的二萘嵌苯-蒽醌对具有高达570的信号/背景比。反应速度也是显著的;在20 ℃下加入底物DNA后5分钟内达到平衡。
In the presence of poly(L-lysine)-graft-dextran, an in-stem molecular beacon involving three perylene-anthraquinone pairs in the stem region had a signal/background ratio of as high as 570. Response speed was also remarkable; equilibrium was attained within 5 minutes after addition of substrate DNA at 20 degrees C.