Traumatic Brain Injury, Chronic Traumatic Encephalopathy, and Alzheimer Disease
Traumatic Brain Injury, Chronic Traumatic Encephalopathy, and Alzheimer Disease
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DOI：
10.1016/j.cger.2018.06.008
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发表时间：
2018-11-01
影响因子：
3.3
通讯作者：
Grossberg, George T.
中科院分区：
文献类型：
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作者：
al-Dahhak, Roula;Khoury, Rita;Grossberg, George T.
创伤性脑损伤（TBI）是一个主要的健康和经济负担。随着人口老龄化的加剧，这一问题预计将继续增加。神经退行性疾病更常见于老年人群，无论TBI史如何。最近的证据继续支持TBI和以后生活中的神经认知下降之间的关系（例如运动员和军人）。本文总结了创伤性脑损伤（无论严重程度如何）对65岁或65岁以上老年人痴呆后期发展的病理和临床影响。
Traumatic brain injury (TBI) is a major health and economic burden. With increasing aging population, this issue is expected to continue to increase. Neurodegenerative disorders are more common with aging population in general regardless of history of TBI. Recent evidence continues to support a relation between a TBI and neurocognitive decline later in life (such as in athletes and military). This article summarizes the pathologic and clinical effects of TBI (regardless of severity) on the later development of dementia in individuals 65 years or older.