Comparison of real-time virtual sonography navigation versus BioJet navigation on magnetic resonance imaging guided prostate needle biopsy: a single institutional analysis
Comparison of real-time virtual sonography navigation versus BioJet navigation on magnetic resonance imaging guided prostate needle biopsy: a single institutional analysis
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磁共振成像引导前列腺穿刺活检中实时虚拟超声导航与 BioJet 导航的比较：单一机构分析
DOI：
10.1089/end.2020.0042
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发表时间：
2020
影响因子：
2.7
通讯作者：
Takahiro Yasui
中科院分区：
文献类型：
--
作者：
Takashi Nagai;Taku Naiki;Shuzo Hamamoto;Toshiki Etani;Aya Naiki-Ito;Motoo Nakagawa;Keitaro Iida;Shoichiro Iwatsuki;Kazumi Taguchi;Tetsuji Maruyama;Noriyasu Kawai;Satoru Takahashi;Takahiro Yasui
目的：分析实时虚拟超声（RVS）与biojet导航在mri引导下前列腺穿刺活检的有效性和并发症发生率。方法：我们回顾性分析了我院171例接受mri引导前列腺穿刺活检的患者。前列腺特异性抗原水平为bb0 4.0 ng/mL且多参数MRI （mpMRI）有可疑前列腺癌（PCa）病变的患者行2核MRI引导下的靶向活检（TB）， MRI引导下的TB: RVS和BioJet。RVS导航同步mpMRI图像与经直肠超声（TRUS）图像。BioJet导航使用了一个软件程序，将mpMRI和TRUS的图像合并在一起，生成合成图像。我们回顾性地比较了这两种导航系统的PCa检出率和严重不良事件（ae）的频率，重点是患者。此外，我们比较了两种导航系统在mri引导下结核核的解剖位置（过渡区[TZ]或外周区[PZ]）的检出率。结果：RVS和BioJet活检组的数据分别来自65例和106例患者。其中，RVS-TB包括141个核心（PZ: 49个核心，TZ: 92个核心），BioJet-TB包括276个核心（PZ: 73个核心，TZ: 203个核心）。在检测前列腺癌时，通过对患者进行系统活检和TB，以及ae， RVS和BioJet导航系统之间没有显著差异。此外，两种方法对结核核中PCa的总检出率无显著差异。然而，在TZ中，通过分析mri引导的TB核心，BioJet导航对PCa的检出率明显高于RVS导航（35.0%vs17.4%,p= 0.0023）。结论：在针对TZ病变时，BioJet导航对PCa的检出率高于RVS导航。
Objective:To analyze the effectiveness and complication rate of MRI–guided prostate needle biopsies by using real-time virtual sonography (RVS)vsBioJet navigation.Methods:We retrospectively reviewed 171 patients who underwent an MRI–guided prostate needle biopsy at our institution. Patients whose prostate-specific antigen level was >4.0 ng/mL and who had suspicious prostate cancer (PCa) lesions by multiparametric MRI (mpMRI) underwent 2-core MRI-guided targeted biopsy (TB) and for MRI–guided TB: RVS and BioJet. RVS navigation synchronized mpMRI images with transrectal ultrasound (TRUS) images. BioJet navigation used a software program that merged images from mpMRI and TRUS to produce a composite image. We retrospectively compared the detection rate of PCa and the frequency of severe adverse events (AEs) between these two navigation systems, focusing on patients. In addition, we compared the detection rate of MRI–guided TB cores of two navigation systems regarding anatomical position (transitional zone [TZ] or peripheral zone [PZ]).Results:Data from RVS and BioJet biopsy groups were from 65 and 106 patients, respectively. Of these, RVS-TB included 141 cores (PZ: 49 cores, TZ: 92 cores), and BioJet-TB included 276 cores (PZ: 73 cores, TZ: 203 cores). In detecting PCa, by conducting both systematic biopsy and TB, and AEs in patients, a significant difference was not noted between RVS and BioJet navigation systems. In addition, there was no significant difference in the total detection rate for PCa in TB cores between the two methods. However, in the TZ, BioJet navigation showed a significantly higher detection rate of PCa than RVS navigation (35.0%vs17.4%,p= 0.0023) by analyzing the cores of MRI–guided TB.Conclusion:When targeting TZ lesions, BioJet navigation had a greater detection rate for PCa compared with that of RVS navigation.