DECT Numbers in Upper Abdominal Organs for Differential Diagnosis: A Feasibility Study.
DECT Numbers in Upper Abdominal Organs for Differential Diagnosis: A Feasibility Study.
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DOI：
10.3390/tomography8060225
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发表时间：
2022-11-04
期刊：
影响因子：
--
通讯作者：
Gabata T
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作者：
Toshima F;Yoneda N;Terada K;Inoue D;Gabata T
使用定量双能计算机断层扫描（DECT）数字评估两个实体之间的相似性可能是有用的。然而，基于DECT数字的两个实体之间相似性的标准仍然不清楚。因此，我们考虑了在同一器官内相似的DECT数字可以提供合适的标准的可能性。因此，我们假设单个器官内DECT数量的变化足够小，可以被认为是临床等效的。因此，本初步研究的目的是探讨上腹部器官内DECT数目的差异。这项回顾性研究包括30例肝脏DECT扫描数据的患者。收集以下参数的DECT数：（a, b） 70和40 keV CT值，(c)斜率，(d)有效Z， （e, f）碘和水浓度。从同一器官（肝、脾和肾）的两个感兴趣区域获得的DECT数字的一致性使用Bland-Altman分析评估。每个DECT参数的诊断能力，以区分相同或不同的器官也被评估使用受者操作特征分析。同一器官内95%的一致性界限在延迟期（DP） CT上表现出最小的值范围[(c)−11.2-8.3%,(d)−2.0-1.5%,(e)−11.3-8.4%,(f)−0.59-0.62%]。门静脉（PVP）和DP (DP曲线下面积：0.987-0.999 in （c) - (f)）的DECT数差异，诊断能力显著提高。使用同一器官中DECT数的可变性作为定义相似性的标准，可能有助于通过比较两个实体的DECT数来进行鉴别诊断。
Evaluating the similarity between two entities such as primary and suspected metastatic lesions using quantitative dual-energy computed tomography (DECT) numbers may be useful. However, the criteria for the similarity between two entities based on DECT numbers remain unclear. We therefore considered the possibility that a similarity in DECT numbers within the same organ could provide suitable standards. Thus, we assumed that the variation in DECT numbers within a single organ is sufficiently minimal to be considered clinically equivalent. Therefore, the purpose of this preliminary study is to investigate the differences in DECT numbers within upper abdominal organs. This retrospective study included 30 patients with data from hepatic protocol DECT scans. DECT numbers of the following parameters were collected: (a, b) 70 and 40 keV CT values, (c) slope, (d) effective Z, and (e, f) iodine and water concentration. The agreement of DECT numbers obtained from two regions of interest in the same organ (liver, spleen, and kidney) were assessed using Bland–Altman analysis. The diagnostic ability of each DECT parameter to distinguish between the same or different organs was also assessed using receiver operating characteristic analysis. The 95% limits of agreement within the same organ exhibited the narrowest value range on delayed phase (DP) CT [(c) −11.2–8.3%, (d) −2.0–1.5%, (e) −11.3–8.4%, and (f) −0.59–0.62%]. The diagnostic ability was notably high when using differences in DECT numbers on portal venous (PVP) and DP images (the area under the curve of DP: 0.987–0.999 in (c)–(f)). Using the variability in DECT numbers in the same organ as a criterion for defining similarity may be helpful in making a differential diagnosis by comparing the DECT numbers of two entities.