Normal sperm head morphometric reference values in fertile Asian males
Normal sperm head morphometric reference values in fertile Asian males
复制标题
亚洲生育男性正常精子头部形态参考值
DOI：
10.4103/aja202356
复制
发表时间：
2023
影响因子：
2.9
通讯作者：
Fuping Li
中科院分区：
文献类型：
--
作者：
Yelin Jia;Ying;Lin Yu;Yan Zheng;Ting;Yan;Bin Zhou;Lin Zhang;Fuping Li
Sperm head morphology is crucial for male factor infertility diagnosis and assessment of male reproductive potential. Several criteria are available to analyze sperm head morphology, but they are limited by poor methodology comparability and population applicability. This study aimed to explore comprehensive and new normal morphometric reference values for spermatozoa heads in fertile Asian males. An automated sperm morphology analysis system captured 23 152 stained spermatozoa from confirmed fertile males. Of these samples, 1856 sperm head images were annotated by three experienced laboratory technicians as “normal”. We employed 14 novel morphometric features to describe sperm head size (head length, head width, length/width ratio, and girth), shape (ellipse intersection over union, girth intersection over union, short-axis symmetry, and long-axis symmetry), area (head, acrosome, postacrosomal areas, and acrosome area ratio), and degrees of acrosome and nuclear uniformity. This straight-forward method for the morphometric analysis of sperm by accurate visual measurements is clinically applicable. The measured parameters present valuable information to establish morphometric reference intervals for normal sperm heads in fertile Asian males. The presented detailed measurement data will be valuable for interlaboratory comparisons and technician training. In vitro fertilization and andrology laboratory technicians can use these parameters to perform objective morphology evaluation when assessing male fertilization potential.
CellForm-Human 自动精子形态测定仪的准确度和精密度。
影响因子：
6.7
作者：
Davis,RO;Bain,DE;Siemers,RJ;Thal,DM;Andrew,JB;Gravance,CG
通讯作者：
Gravance,CG