Staphylococcus Aureus Bacteremia in Solid Organ Transplant Recipients: Evidence for Improved Survival When Compared with Nontransplant Patients
Staphylococcus Aureus Bacteremia in Solid Organ Transplant Recipients: Evidence for Improved Survival When Compared with Nontransplant Patients
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DOI：
10.1097/tp.0b013e31824bf219
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发表时间：
2012-05-27
期刊：
影响因子：
6.2
通讯作者：
van Duin, David
中科院分区：
文献类型：
--
作者：
Malinis, Maricar F.;Mawhorter, Steven D.;van Duin, David
背景。金黄色葡萄球菌菌血症（SAB）是发病率和死亡率的重要原因。在此，我们描述了实体器官移植（SOT）后SAB的发病率、临床特征和结果，并将这些特征与非SOT对照进行了比较。在一项单中心回顾性研究中，2000年1月1日至2008年12月31日期间获得了金黄色葡萄球菌阳性的血培养。对所有患有SAB的SOT接受者进行图表审查。采用社会保障死亡指数确定全因死亡率。2959例SAB患者中有70例为SOT受体（肺26例，肝19例，肾18例，心7例）。SOT患者SAB总发病率为22.9/1000。早发性SAB (
Background. Staphylococcus aureus bacteremia (SAB) is an important cause of morbidity and mortality. Herein, we describe the incidence, clinical characteristics, and outcomes of SAB after solid organ transplantation (SOT) and compare these features with non-SOT controls.Methods. In a single-center retrospective study, blood cultures positive for S. aureus were obtained from January 1, 2000, to December 31, 2008. Chart review was performed on all SOT recipients with SAB. The social security death index was used to determine all-cause mortality.Results. Seventy of 2959 patients with SAB were SOT recipients (26 lung, 19 liver, 18 kidney, and seven heart). The overall attack rate of SAB in SOT was 22.9/1000 transplant patients. Early-onset SAB (