INTRACELLULAR ANALYSIS OF TRIGEMINAL MOTONEURON ACTIVITY DURING SLEEP IN CAT

INTRACELLULAR ANALYSIS OF TRIGEMINAL MOTONEURON ACTIVITY DURING SLEEP IN CAT
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DOI:
10.1126/science.202025
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发表时间:
1978-01-01
期刊:
影响因子:
56.9
通讯作者:
CHASE, MH
CHASE, MH
中科院分区:
综合性期刊1区
文献类型:
--
作者:
NAKAMURA, Y;GOLDBERG, LJ;CHASE, MH

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细胞内记录正常呼吸,未麻醉的猫在自然发生的睡眠三叉神经运动神经元。从安静到活跃睡眠的过渡伴随着紧张性运动神经元超极化。刺激网状结构引起的三叉神经运动神经元在安静的睡眠和超极化电位在活跃的睡眠过程中去极化电位。这些结果为网状反应逆转现象提供了一个突触学解释,并为睡眠状态下控制运动活动的基本机制提供了新的见解。
Intracellular recordings were made from trigeminal motoneurons of normally respiring, unanesthetized cats during naturally occurring sleep. The transition from quiet to active sleep was accompanied by tonic motoneuron hyperpolarization. Stimulation of the reticular formation induced a depolarizing potential in trigeminal motoneurons during quiet sleep and a hyperpolarizing potential during active sleep. The results provide a synaptic explanation for the phenomenon of reticular response reversal and insights into the basic mechanisms controlling motor activity during the sleep states.