EXPERIMENTAL INDUCTION OF DISCIFORM KERATITIS.
EXPERIMENTAL INDUCTION OF DISCIFORM KERATITIS.
复制标题
盘状角膜炎的实验诱导。
DOI：
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发表时间：
1965
期刊：
影响因子：
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通讯作者：
H. Kaufman
中科院分区：
文献类型：
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作者：
L. E. Williams;A. Nesburn;H. Kaufman
角膜炎是Fuchs在1901年引入的术语，用于描述中央角膜混浊，最常见的是单纯疱疹性角膜炎的晚期并发症。1临床上，单纯疱疹感染后可发生两种间质病变。在一种类型中，出现致密的、白色、干酪样混浊，其通常是偏心的。这些病变的发病机制似乎与典型的类风湿性病变不同。角膜水肿的特征是角膜水肿的圆形斑块，通常位于中央，通常被正常角膜包围。在角膜的受累区域，后弹力层有褶皱，基质肿胀，常伴有上皮大疱。在早期阶段，水肿状病变是可逆的，但随着水肿持续，角膜瘢痕和永久性混浊往往发展。虽然角膜单纯疱疹后角膜炎的确切发病率尚不清楚，但在1956年，
Disciform keratitis is a term introduced by Fuchs in 1901 to describe a central corneal opacification that is seen most often as a late complication of herpes simplex keratitis. 1 Clinically, two kinds of stromal disease may occur after herpes simplex infection. In one type, dense, white, cheesy opacities which are generally eccentric occur. The pathogenesis of these lesions appears to be different from those of the typical disciform lesion. The disciform lesion is characterized by a round patch of corneal edema which is generally central and is typically surrounded by normal cornea. In the involved area of cornea, there are folds in Descemet's membrane, swelling of the stroma, and often epithelial bullae. In the early stages the disciform lesion is reversible, but as the edema persists, corneal scarring and permanent opacities often develop. Although the exact incidence of disciform keratitis following corneal herpes simplex is not known, in 1956,