Role of tubulin and dynein in spermatozoan motility

Role of tubulin and dynein in spermatozoan motility
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微管蛋白和动力蛋白在精子活力中的作用

DOI:
10.1002/mrd.1080360214
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发表时间:
1993
影响因子:
2.5
通讯作者:
H. Mohri
H. Mohri
中科院分区:
生物学3区
文献类型:
--
作者:
H. Mohri

文献摘要

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在大多数动物中,精子的运动依赖于鞭毛,鞭毛包含所谓的9+2结构,即一对中央单线微管,由9个外部双线微管环绕,共同构成轴丝。每个外二联体由一个完整的A形小管和一个C形B形小管组成。一对外臂和内臂从A管向相邻的B管伸出。其他突起被称为径向辐条,附着在A管上,并向中央鞘突起延伸,中央鞘突起与中央对相连。外二联体通过连接蛋白或二联体间连接相互连接。在哺乳动物中,9+2复合体外有9个粗纤维。
Movement of spermatozoa in most animal species depends on their flagella, which contain the so-called 9 + 2 structure, a pair of central singlet microtubules that are encircled by nine outer doublet microtubules and that together constitute the axoneme. Each outer doublet consists of a complete A-tubule and a C-shaped B-tubule. From the A-tubule, a pair of outer and inner arms project toward the adjacent B-tubule. Other projections called radial spokes attach to the A-tubule and extend toward the central sheath projections, which are bound to the central pair. The outer doublets are connected with each other by nexin or interdoublet links. In mammals, there are nine coarse fibers outside the 9 + 2 complex.