Obesogens and Obesity: State-of-the-Science and Future Directions Summary from a Healthy Environment and Endocrine Disruptors Strategies Workshop
Obesogens and Obesity: State-of-the-Science and Future Directions Summary from a Healthy Environment and Endocrine Disruptors Strategies Workshop
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DOI：
10.1016/j.ajcnut.2023.05.024
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发表时间：
2023-07-03
影响因子：
7.1
通讯作者：
Blumberg, Bruce
中科院分区：
文献类型：
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作者：
Heindel, Jerrold J.;Alvarez, Jessica A.;Blumberg, Bruce
在2022年9月7日和8日，健康环境和内分泌干扰物战略，一个环境健康科学项目，召集了一个科学研讨会，涉及肥胖、毒理学或肥胖研究的相关利益相关者，回顾了关于肥胖化学物质可能导致肥胖流行的作用的科学现状。研讨会的目的是研究支持肥胖因子导致人类肥胖的假说的证据；讨论如何更好地理解、接受和传播导致肥胖大流行的致肥因子；并考虑未来研究和潜在缓解战略的必要性。本报告详细介绍了讨论情况、达成共识的关键领域以及预防肥胖的未来机会。与会者一致认为，环境致肥物是真实的、重要的，在一定程度上导致了个人体重增加，在社会层面上导致了全球肥胖和代谢性疾病的流行；此外，至少在理论上，这是可以补救的。
On September 7 and 8, 2022, Healthy Environment and Endocrine Disruptors Strategies, an Environmental Health Sciences program, convened a scientific workshop of relevant stakeholders involved in obesity, toxicology, or obesogen research to review the state of the science regarding the role of obesogenic chemicals that might be contributing to the obesity pandemic. The workshop's objectives were to examine the evidence supporting the hypothesis that obesogens contribute to the etiology of human obesity; to discuss opportunities for improved understanding, acceptance, and dissemi-nation of obesogens as contributors to the obesity pandemic; and to consider the need for future research and potential mitigation strategies. This report details the discussions, key areas of agreement, and future opportunities to prevent obesity. The attendees agreed that environmental obesogens are real, significant, and a contributor at some degree to weight gain at the individual level and to the global obesity and metabolic disease pandemic at a societal level; moreover, it is at least, in theory, remediable.