The Neurobiology of Anesthetic Emergence.
The Neurobiology of Anesthetic Emergence.
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DOI：
10.1097/ana.0000000000000212
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发表时间：
2016-07
影响因子：
3.7
通讯作者：
Mashour GA
中科院分区：
文献类型：
--
作者：
Tarnal V;Vlisides PE;Mashour GA
对于神经外科患者来说，实现平稳和快速的全麻苏醒是特别重要的，也是神经麻醉学家的临床目标。最近的数据表明，涌现的过程不仅仅是归纳的镜像，而是由不同的神经回路控制的。在这篇叙述性综述中，我们讨论了（1）滞后，（2）神经惯性的概念，（3）诱导和涌现的神经生物学之间的不对称性，以及（4）最近积极诱导涌现的尝试。
Achieving a smooth and rapid emergence from general anesthesia is of particular importance for neurosurgical patients and is a clinical goal for neuroanesthesiologists. Recent data suggest that the process of emergence is not simply the mirror image of induction, but rather controlled by distinct neural circuits. In this narrative review, we discuss (1) hysteresis, (2) the concept of neural inertia, (3) the asymmetry between the neurobiology of induction and emergence, and (4) recent attempts at actively inducing emergence.