Tumors and Tumorous Conditions of the Bones and Joints

Tumors and Tumorous Conditions of the Bones and Joints
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骨骼和关节的肿瘤和肿瘤状况

DOI:
10.1097/00007611-195906000-00046
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发表时间:
1959
期刊:
The Yale Journal of Biology and Medicine
影响因子:
--
通讯作者:
W. Ober
W. Ober
中科院分区:
--
文献类型:
--
作者:
W. Ober

文献摘要

被引文献

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一本关于病理学特殊分支的教科书的大部分价值在于它将病理解剖学与临床观察相关联的能力。Jaffe博士在纽约的关节病医院担任病理学家已有30年,他是一位向骨科医生解释骨病理学事实和推测的大师,同样擅长向他的病理学家同事合理解释骨肿瘤的研究、诊断和管理的临床紧急情况。原发性骨肿瘤在实验室中并不常见。由于他的地位,贾菲博士的命运是负责照顾,保存,以及研究数量异常庞大的此类标本,其中许多是一生中遇到一次的那种。采用理性和经验的方法,作者已经完成了自己的任务,概括已知的事实材料有关骨肿瘤和相关病变的崇高。在这个目标之上,他实现了一个清晰的综合临床,放射学和病理学特征的每一个肿瘤实体考虑。值得称道的是,他还能够为他的读者吸收和评价这一领域已经发表的大量理论材料,这些材料可能会在该领域占据主导地位多年。文本巧妙地支持了近200个整版,每个包含几个单独的插图。说明性材料包括X射线、大体标本和精心挑选的显微镜视野。在许多情况下,大体标本与所讨论的病变的X线片并列,并且人们不仅可以看到外表面,还可以看到放射平面上的切割面。所有的板块都是正面排列的,传说是反面的;因此,插图的空间并没有牺牲给传说,传说非常详细。实际上,不理解正在发生的事情就不可能看到这些图片。选择微观领域和裁剪印刷品总是一件痛苦而耗时的事情。作者的努力没有白费;没有边缘模糊的图片,没有错误的组织学技术的证据,对比度差,笨拙的组成,等等。同样高标准的选择也适用于X光片。对于已经熟悉骨肿瘤文献的读者来说,有许多引人入胜的段落。其中之一是在分类上的巨大进步,其中贾菲远远超出了费米斯特的模式,目前在许多圈子里流行。有直言不讳的声明说,威利斯的怀疑存在这样一个实体尤因的肿瘤已被证明是没有道理的,一个声明的教条主义作为那些英国大师和基于更多的证据。在一个简短的段落Jaffe把奥尔布赖特的疾病(骨纤维异常增殖症与性早熟,异常色素沉着等)。透视:“。. .对于每一个florid(Albright)类型的病例,大约有30或40个病例。. .其中骨骼的纤维发育异常受累有限。. .与任何显著的皮肤色素沉着无关,显然与骨骼早熟无关,当然也与性早熟无关。尽管人数不多,但
Much of the value of a text dealing with a special branch of pathology lies in its ability to correlate morbid anatomy with clinical observations. Dr. Jaffe, who has been pathologist to the Hospital for Joint Diseases in New York for three decades, is a master at explaining the facts and speculations of bone pathology to orthopedic surgeons and is equally adroit at rationalizing the clinical exigencies which govern the study, diagnosis, and management of bone tumors to his fellow pathologists. Primary neoplasms of bone are not common fare in the laboratory. By virtue of his position, it has fallen to Dr. Jaffe's lot to be responsible for the care, preservation, and study of an uncommonly large number of such specimens, many of which are of the sort that one encounters once in a lifetime. Employing a rational and empirical approach, the author has acquitted himself nobly of the task of epitomizing the known factual material about bone tumors and related lesions. Over and above this goal, he achieves a lucid synthesis of clinical, radiological, and pathological features of each neoplastic entity considered. It is much to his credit that he has been able also to assimilate and evaluate for his readers the large volume of theoretical material which has been published in this field and will probably dominate the field for many years. The text is ably supported by almost 200 full-page plates, each containing several separate illustrations. The illustrative material includes x-rays, gross specimens, and well chosen microscopic fields. In many instances gross specimens are presented in juxtaposition to the x-ray of the lesion in question, and one is privileged to see not only the external surface but the cut surface in the radiological plane. All the plates are arranged recto, the legends being verso; space for illustration is therefore not sacrificed to legends, and the legends are extremely detailed. It is practically impossible to look at the pictures without understanding what is going on. The selection of microscopic fields and the cropping of prints is always a painful and timeconsuming business. The author's efforts have not been wasted; there are no pictures with blurred margins, no evidence of faulty histological technique, poor contrast, awkward composition, etc. The plates are a delight to the microscopist's eye. The same high standard of selection applies to the roentgenograms. For the reader already familiar with the literature on bone tumors there are many fascinating passages. Among these is the large stride in classification in which Jaffe goes far beyond Phemister's schema, currently in vogue in many circles. There is the blunt statement that Willis's doubts regarding the existence of such an entity as Ewing's tumor have turned out to be unjustified, a statement as dogmatic as those of the British master and based on more evidence. In one short paragraph Jaffe puts Albright's disease (fibrous dysplasia of bone associated with precocious puberty, abnormal pigmentation, etc.) into perspective: ". . . for every case of the florid (Albright) type there are about 30 or 40 cases . . . in which the fibrodysplastic involvement of the skeleton is limited . . . and is not associated with any striking cutaneous pigmentation, apparently not with skeletal precocity, and certainly not with sexual precocity. In spite of their small number, these