A novel two-dimensional quantitative shear wave elastography for differentiating malignant from benign breast lesions.
A novel two-dimensional quantitative shear wave elastography for differentiating malignant from benign breast lesions.
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发表时间：
2015-07
影响因子：
0.1
通讯作者：
L. Tang;Hui-Xiong Xu;Xiaowan Bo;Bo-Ji Liu;Xiao-Long Li;Rong Wu;Dan-Dan Li-Dan;Lin Fang;Xiao-hong Xu
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文献类型：
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作者：
L. Tang;Hui-Xiong Xu;Xiaowan Bo;Bo-Ji Liu;Xiao-Long Li;Rong Wu;Dan-Dan Li-Dan;Lin Fang;Xiao-hong Xu
目的评价一种新型的定量剪切波弹性成像（SWE）虚拟触摸组织成像量化（VTIQ）在乳腺病变诊断中的应用价值。方法对98例经病理证实的乳腺病变133例进行常规超声和VTIQ影像学检查。乳腺病变按美国乳腺影像学报告和数据系统（BI-RADS）分类。获得病变VTIQ的最大、最小、平均和中位数横波速度（SWV）值。计算受者工作曲线下面积（AUC）。结果133例病变中，恶性26例，良性107例。美国BI-RADS评估的敏感性和特异性分别为96.2%和62.6%。恶性病变的SWVs均显著高于良性病变（P < 0.05）。平均SWV的临界值为3.68 m/s，敏感性和特异性分别为93.3%和79.4%。结论新的VTIQ定量SWE有助于乳腺病变的鉴别。在美国BI-RADS评估中加入VTIQ的定量SWE可提高诊断乳腺病变的特异性，同时又不失敏感性。
OBJECTIVE The purpose of this study was to evaluate the diagnostic performance of a novel quantitative shear wave elastography (SWE) of virtual touch tissue imaging quantification (VTIQ) in diagnosis of breast lesions. METHODS The conventional ultrasound (US) and VTIQ images of 133 pathologically proven breast lesions in 98 patients were assessed. The breast lesions were classified by US breast imaging reporting and data system (BI-RADS) category. The maximum, minimum, mean and median shear wave velocity (SWV) values on VTIQ in the lesions were obtained. The area under the receiver operating curve (AUC) was computed. RESULTS Twenty-six of 133 lesions were malignant and 107 were benign. The sensitivity and specificity for US BI-RADS assessment were 96.2% and 62.6% respectively. The SWVs in malignant lesions were all significantly higher than those in benign ones (all P 0.05). The cut-off value of mean SWV was 3.68 m/s, with associated sensitivity and specificity of 93.3% and 79.4% respectively. CONCLUSION The novel quantitative SWE of VTIQ is helpful in differentiating breast lesions. Adding the quantitative SWE of VTIQ to the US BI-RADS assessment improves the specificity in diagnosing breast lesions without loss of sensitivity.