Biosynthetic Polymers as Functional Materials.
Biosynthetic Polymers as Functional Materials.
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DOI：
10.1021/acs.macromol.6b00439
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发表时间：
2016-06-28
期刊：
影响因子：
5.5
通讯作者：
Gianneschi NC
中科院分区：
文献类型：
--
作者：
Carlini AS;Adamiak L;Gianneschi NC
The synthesis of functional polymers encoded with biomolecules has been an extensive area of research for decades. As such, a diverse toolbox of polymerization techniques and bioconjugation methods has been developed. The greatest impact of this work has been in biomedicine and biotechnology, where fully synthetic and naturally derived biomolecules are used cooperatively. Despite significant improvements in biocompatible and functionally diverse polymers, our success in the field is constrained by recognized limitations in polymer architecture control, structural dynamics, and biostabilization. This Perspective discusses the current status of functional biosynthetic polymers and highlights innovative strategies reported within the past five years that have made great strides in overcoming the aforementioned barriers.
