Controlled Incorporation of Particles into the Central Portion of Vesicle Walls
Controlled Incorporation of Particles into the Central Portion of Vesicle Walls
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DOI：
10.1021/ja1024063
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发表时间：
2010-07-28
影响因子：
15
通讯作者：
Eisenberg, Adi
中科院分区：
文献类型：
--
作者：
Mai, Yiyong;Eisenberg, Adi
由于囊泡的潜在应用以及人们对囊泡结构的内在兴趣，近年来囊泡引起了人们极大的关注。将各种颗粒掺入囊泡壁也受到了关注。在这种情况下，未解决的问题之一是颗粒仅受控地结合到囊泡壁的中央部分，即外部和内部界面之间的大约一半。在本文中，我们描述了一种一般的方法，只将颗粒掺入囊泡壁的中央部分，即中央10%-20%。该策略涉及使用两嵌段共聚物作为颗粒上的涂层，其结构类似于泡囊成形器的结构，这允许颗粒优先定位在壁的中央部分。
Vesicles have attracted considerable attention recently because of many potential applications as well as intrinsic interest in the structures. The incorporation of various particles into vesicle walls has also received attention. One of the unsolved problems, in this context, is the controlled incorporation of particles into only the central portion of the vesicle walls, i.e. approximately halfway between the external and internal interfaces. In this paper, we describe a general method for the incorporation of particles into only the central portion, i.e. central 10-20%, of the vesicle walls. The strategy involves the use, as coatings on the particles, of diblock copolymers of a structure similar to that of the vesicle formers, which allows the particles to be preferentially localized in the central portion of the walls.