Microdosimetry of neutron field for boron neutron capture therapy at Kyoto University Reactor
Microdosimetry of neutron field for boron neutron capture therapy at Kyoto University Reactor
复制标题
DOI：
10.1093/rpd/nch150
复制
发表时间：
2004-01-01
影响因子：
1
通讯作者：
Shizuma, K
中科院分区：
文献类型：
--
作者：
Endo, S;Onizuka, Y;Shizuma, K
在京都大学反应堆（KUR）的临床BNCT场，测量了由丙烯酸体模模拟的人体微剂量单粒子谱。由初始反应和随后的相互作用产生的反冲粒子，即质子、电子、α粒子和碳核在微剂量谱中被识别。从质子，α粒子和碳的中子剂量的相对贡献估计为约0.9，0.07和0.3，分别为5和41毫米之间的四个深度。我们估计，剂量平均线性能量，y（D）随深度从64到46千电子伏妈妈（-1）。相对生物有效性（RBE）的这个中子场使用的微剂量谱的响应函数，估计减少从3.6到2.9，随着深度的增加。
Microdosimetric single event spectrum in a human body simulated by an acrylic phantom has been measured for the clinical BNCT field at the Kyoto University Reactor (KUR). The recoil particles resulting from the initial reaction and subsequent interactions, namely protons, electrons, alpha particles and carbon nuclei are identified in the microdosimetric spectrum. The relative contributions to the neutron dose from proton, alpha particles and carbon are estimated to be about 0.9, 0.07 and 0.3, respectively, four depths between 5 and 41 mm. We estimate that the dose averaged lineal energy, y(D) decreased with depth from 64 to 46 keV mum(-1). Relative biological effectiveness (RBE) of this neutron field using a response function for the microdosimetric spectrum was estimated to decrease from 3.6 to 2.9 with increasing depth.