Au-Fe3O4 dumbbell nanoparticles as dual-functional probes
Au-Fe3O4 dumbbell nanoparticles as dual-functional probes
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DOI：
10.1002/anie.200704392
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发表时间：
2008-01-01
影响因子：
16.6
通讯作者：
Sun, Shouheng
中科院分区：
文献类型：
--
作者：
Xu, Chenjie;Xie, Jin;Sun, Shouheng
含不同官能团的哑铃形纳米粒子的合成是近年来研究的热点。[1]在这样的哑铃结构中，一个纳米颗粒连接到另一个纳米颗粒，并且通过结的电子通信可以彻底改变局部电子结构，导致催化，磁性和光学特性的额外控制维度。[2]此外，哑铃状结构提供了两个功能表面，用于连接不同种类的分子，使这些物种作为诊断和治疗应用的多功能探针特别有吸引力。[3]Au-Fe 3 O 4纳米颗粒代表了一种这样的多功能系统。它们含有Au和Fe 3 O 4纳米颗粒，已知它们具有生物相容性，并已广泛用于生物医学中的光学和磁性应用。[4]与传统的单组分Au或Fe_3 O_4纳米粒子相比，哑铃状Au-Fe_3 O_4体系具有明显的优点：1）结构
Synthesis of dumbbell-shaped nanoparticles containing different functionalities has attracted much attention recently.[1] In such a dumbbell structure, one nanoparticle is linked to another, and electronic communication across the junction can drastically change the local electronic structure, leading to an additional dimension of control in catalytic, magnetic, and optical properties.[2] Moreover, the dumbbell structure offers two functional surfaces for the attachment of different kinds of molecules, making such species especially attractive as multifunctional probes for diagnostic and therapeutic applications.[3] Au-Fe3O4 nanoparticles represent one such multifunctional system. They contain both Au and Fe3O4 nanoparticles, which are known to be biocompatible and have been used extensively for optical and magnetic applications in biomedicine.[4] Compared with conventional single-component Au or Fe3O4 nanoparticles, the dumbbell-like Au-Fe3O4 systems have distinct advantages: 1) The structure