The impact of surgical sperm retrieval on the in vitro fertilization outcomes of infertile patients with temporary ejaculation failure on their oocyte retrieval day
The impact of surgical sperm retrieval on the in vitro fertilization outcomes of infertile patients with temporary ejaculation failure on their oocyte retrieval day
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手术取精对暂时性射精失败的不孕症患者取卵日体外受精结果的影响
DOI：
10.1016/j.fertnstert.2012.10.003
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发表时间：
2013-02-01
影响因子：
6.7
通讯作者：
Qiao Jie
中科院分区：
文献类型：
--
作者：
Li Junsheng;Bai Quan;Qiao Jie
目的：探讨睾丸抽精对试管婴儿（IVF）患者暂时性射精失败（TEF）取卵当日临床结局的影响。设计：病例对照研究。地点：大学附属试管婴儿中心。患者：108对不孕夫妇在取卵当天遭遇TEF。干预措施：采用睾丸抽精和卵浆内单精子注射（TESA-ICSI）帮助TEF夫妇完成IVF治疗。选择一组阻塞性无精子症（OA）患者作为对照组，评估该干预措施的有效性和安全性。主要观察指标：受精率、可移植胚胎率和临床妊娠率（pr）。结果：通过TESA-ICSI， TEF夫妇每个试管婴儿周期的临床PR达到38.83%（40/103）。与OA组相比，TEF组解冻ET周期的受精率（66.43% vs. 65.25%）、可移植胚胎率（60.76% vs. 60.85%）和PR （51.61% vs. 50.00%）相当，但新鲜ET周期的PR （25.49% vs. 44.64%）相对较低。结论：TESA-ICSI是一种相对有效、安全的治疗TEF的方法。[j] .中国农业科学（英文版），2013;39(5):662 - 662。(C) 2013年由美国生殖医学学会出版。)
Objective: To evaluate the impact of testicular sperm aspiration on the clinical outcomes of IVF patients with temporary ejaculation failure (TEF) on the day of oocyte retrieval.Design: A case-control study.Setting: University-affiliated IVF center.Patient(s): One hundred eight infertile couples encountering TEF on the day of oocyte retrieval.Intervention(s): Testicular sperm aspiration and intracytoplasmic sperm injection (TESA-ICSI) were employed to help the TEF couples to complete their IVF treatments. A group of obstructive azoospermia (OA) patients was chosen as a control group to evaluate the efficiency and safety of this intervention.Main Outcome Measure(s): Fertilization rates, transferable embryo rates, and clinical pregnancy rates (PRs).Result(s): Through the TESA-ICSI, TEF couples achieved a 38.83% (40/103) clinical PR per IVF cycle. Compared with the OA group, the TEF group showed a comparable fertilization rate (66.43% vs. 65.25%), transferable embryo rate (60.76% vs. 60.85%), and PR (51.61% vs. 50.00%) in thawed ET cycles but a relatively low PR (25.49% vs. 44.64%) in fresh ET cycles.Conclusion(s): TESA-ICSI is a relatively efficient and safe way to help the patients encountering TEF. (Fertil Steril (R) 2013;99:362-6. (C) 2013 by American Society for Reproductive Medicine.)