Synthesis of Copper Nanoparticles by Thermal Decomposition and Their Antimicrobial Properties
Synthesis of Copper Nanoparticles by Thermal Decomposition and Their Antimicrobial Properties
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DOI：
10.1155/2014/980545
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发表时间：
2014-01-01
影响因子：
--
通讯作者：
Garcia-Cerda, L. A.
中科院分区：
文献类型：
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作者：
Betancourt-Galindo, R.;Reyes-Rodriguez, P. Y.;Garcia-Cerda, L. A.
以氯化铜、油酸钠和苯醚为溶剂，采用热分解法合成了纳米铜粒子。通过X射线衍射和透射电子显微镜证实了纳米粒子的形成。XRD图中的峰对应于金属铜的面心立方（fcc）结构的标准值，并且没有检测到其它杂质结晶相的峰。TEM分析显示球形纳米颗粒的尺寸在4至18 nm的范围内。以金黄色葡萄球菌和铜绿假单胞菌为实验菌，研究了纳米铜粒子的体外抗菌性能。热分解法制备的纳米铜颗粒对这些高度耐药的细菌有明显的抑制作用。
Copper nanoparticles were synthesized by thermal decomposition using copper chloride, sodium oleate, and phenyl ether as solvent agents. The formation of nanoparticles was evidenced by the X-ray diffraction and transmission electron microscopy. The peaks in the XRD pattern correspond to the standard values of the face centered cubic (fcc) structure of metallic copper and no peaks of other impurity crystalline phases were detected. TEM analysis showed spherical nanoparticles with sizes in the range of 4 to 18 nm. The antibacterial properties of copper nanoparticles were evaluated in vitro against strains of Staphylococcus aureus and Pseudomonas aeruginosa. The antibacterial activity of copper nanoparticles synthesized by thermal decomposition showed significant inhibitory effect against these highly multidrug-resistant bacterial strains.