P-wave duration and dispersion in patients with coronary slow flow and its relationship with Thrombolysis in Myocardial Infarction frame count
P-wave duration and dispersion in patients with coronary slow flow and its relationship with Thrombolysis in Myocardial Infarction frame count
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DOI：
10.1016/j.jelectrocard.2006.06.004
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发表时间：
2008-01-01
影响因子：
1.3
通讯作者：
Cam, Fatih
中科院分区：
文献类型：
--
作者：
Dogan, Sait M.;Yidirim, Nesligul;Cam, Fatih
目的：据报道，P 波色散 (PD) 和持续时间与正弦脉冲的不均匀和不连续传播有关。本研究的目的是调查冠状动脉慢血流 (CSF) 现象患者的 PD。 方法：研究人群包括 48 名经血管造影证明冠状动脉正常且所有 3 条冠状血管均存在慢冠脉血流的患者（第 1 组，36 名男性；平均年龄，54±9 岁）和 32 名经血管造影证明冠状动脉正常但不伴有慢冠脉血流的受试者（第 11 组，24 名男性，平均年龄，53±10 岁）。通过心肌梗塞溶栓 (TIMI) 帧计数记录所有患者和对照受试者的冠状动脉流速。 I 组中所有患者的 TIMI 帧计数比对照组（第 11 组）高出 2 个 SD 以上。通过将每个主要心外膜冠状动脉的 TIMI 帧计数相加，然后将获得的值除以 3，计算每位患者和对照受试者的平均 TIMI 帧计数。从 12 导联表面心电图测量最大和最小 P 波持续时间（P-max 和 P-min）和 PD。并进行超声心动图检查。结果：2组患者年龄、性别、高血压、糖尿病、高脂血症、吸烟情况差异无统计学意义（P>0.05）。发现 CSF 患者的 P 波离散度和 P-max 显着高于对照受试者（分别为 39.4 +/- 17 与 21.2 +/- 10 毫秒和 121.6 +/- 17.1 与 104.3 +/- 10.4 毫秒；P < .0001）。此外，我们发现 P-max 和 PD 与平均 TIMI 帧计数之间存在显着正相关（分别为 r = 0.836 和 r = 0.806；P < .0001）。 结论：发现 CSF 患者的 P 波离散度和 P 波持续时间均大于对照组。 (C) 2008 Elsevier Inc. 保留所有权利。
Aim: P-wave dispersion (PD), and duration has been reported to be associated with inhomogeneous and discontinuous propagation of sinus impulses. The aim of this study was to investigate the PD in patients with coronary slow flow (CSF) phenomenon.Methods: Study population included 48 patients with angiographically proven normal coronary arteries and slow coronary flow in all 3 coronary vessels (group 1, 36 men; mean age, 54 9 years) and 32 subjects with angiographically proven normal coronary arteries without associated slow coronary flow (group 11, 24 men, mean age, 53 10 years). Coronary flow rates of all patients and control subjects were documented by Thrombolysis In Myocardial Infarction (TIMI) frame count. All patients in group I had TIMI frame counts greater than 2 SD above those of control subjects (group 11). The mean TIMI frame count for each patient and control subject was calculated by adding the TIMI frame counts for each major epicardial coronary artery and then dividing the obtained value into 3. The maximum and minimum P-wave duration (P-max and P-min) and PD were measured from the 12-lead surface electrocardiogram. Echocardiographic examination was also performed.Results: There was no statistically significant difference between the 2 groups with respect to age, sex, hypertension, diabetes mellitus, hyperlipidemia, and cigarette smoking (P > .05). P-wave dispersion and P-max of patients with CSF were found to be significantly higher than those of control subjects (39.4 +/- 17 vs 21.2 +/- 10 milliseconds and 121.6 +/- 17.1 vs 104.3 +/- 10.4 milliseconds, respectively; P < .0001). Moreover, we found a significant positive correlation between both P-max and PD with mean TIMI frame count (r = 0.836 and r = 0.806, respectively; P < .0001).Conclusions: P-wave dispersion and P-wave duration both were found to be greater in patients with CSF than in controls. (C) 2008 Elsevier Inc. All rights reserved.