Facial affect recognition training in autism:: Can we animate the fusiform gyrus?
Facial affect recognition training in autism:: Can we animate the fusiform gyrus?
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DOI：
10.1037/0735-7044.120.1.211
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发表时间：
2006-02-01
影响因子：
1.9
通讯作者：
Poustka, F
中科院分区：
文献类型：
--
作者：
Bölte, S;Hubl, D;Poustka, F
在自闭症的神经科学中，最一致的发现之一是在面部处理过程中梭状回（FG）的低激活。在这项研究中，作者研究了成功的面部情感识别训练是否与自闭症患者FG激活增加有关。在10名高功能自闭症患者中，研究了一个基于计算机的程序来教授面部情感识别的效果。在训练前和训练后，对FG和其他感兴趣区域的血氧水平依赖性（BOLD）功能磁共振成像（fMRI）变化以及行为面部影响识别措施进行了评估。在FG中未观察到显著的活化变化。经过训练的参与者表现出行为改善，伴随着上级顶叶更高的BOLD功能磁共振成像信号，并保持右侧内侧枕回的激活。
One of the most consistent findings in the neuroscience of autism is hypoactivation of the fusiform gyrus (FG) during face processing. In this study the authors examined whether successful facial affect recognition training is associated with an increased activation of the FG in autism. The effect of a computer-based program to teach facial affect identification was examined in 10 individuals with high-functioning autism. Blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging (fMRI) changes in the FG and other regions of interest, as well as behavioral facial affect recognition measures, were assessed pre- and posttraining. No significant activation changes in the FG were observed. Trained participants showed behavioral improvements, which were accompanied by higher BOLD fMRI signals in the superior parietal lobule and maintained activation in the right medial occipital gyrus.