Comparison of sperm viability with seminal plasma metal levels

Comparison of sperm viability with seminal plasma metal levels
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DOI:
10.1007/bf02783337
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发表时间:
1998-06-01
影响因子:
3.9
通讯作者:
Powell, LC
Powell, LC
中科院分区:
生物学3区
文献类型:
--
作者:
Dawson, EB;Ritter, S;Powell, LC

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本研究比较了64名表面健康男性精液中铅(Pb)、镉(Cd)和铝(Al)与活精子的关系。将测量水平分为活精子计数三分位数(50% [20例受试者])。计算每组的平均值+/- SD,并通过ANOVA比较高三分位数和低三分位数的平均值之间的差异。高、低活精子组间铅、铝含量差异显著(p < 0.01、p < 0.05),镉含量差异不显著(p> 0.05)。精子活率与精浆金属含量呈斯皮尔曼等级相关,与Mg呈显著正相关(p < 0.05)。然而,与铅(p < 0.001)、镉(p < 0.01)和铝(p < 0.01)呈负相关。Ca和Zn之间无显著相关性。精子活率与精液中三种金属含量的直线回归分析表明,金属含量与精子活率呈负相关(P < 0.001),
This study compares the semen levels of lead (Pb), cadmium (Cd), and aluminum (Al) in relation to live sperm in semen samples from 64 apparently healthy men. The measured levels were separated into live sperm count tertiles (50% [20 subjects]). The mean +/- SD for each group was calculated, and the difference between the means of the high and low tertiles were compared by ANOVA. Significant differences were observed between the high and low live sperm groups for Pb (p < 0.01) and Al (p < 0.05), but not Cd. Spearman's rank correlation between sperm viability and the semen plasma metal levels showed a direct relation to Mg (p < 0.05). However, there was an inverse relation to lead (p < 0.001), cadmium (p < 0.01), and aluminum (p < 0.01). There was no significant correlation between Ca and Zn. Linear regression between the live sperm counts and semen level of the three metals show that metal levels were inversely correlated with the percentage of live sperm (p < 0.001,