Rhipicephalus (Boophilus) microplus:: Distinct acute phase proteins vary during infestations according to the genetic composition of the bovine hosts, Bos taurus and Bos indicus
Rhipicephalus (Boophilus) microplus:: Distinct acute phase proteins vary during infestations according to the genetic composition of the bovine hosts, Bos taurus and Bos indicus
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DOI：
10.1016/j.exppara.2007.10.006
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发表时间：
2008-04-01
影响因子：
2.1
通讯作者：
Ferreira de Miranda Santos, Isabel K.
中科院分区：
文献类型：
--
作者：
Carvalho, Wanessa Araujo;Bechara, Gervasio Henrique;Ferreira de Miranda Santos, Isabel K.
蜱虫叮咬可能会引发急性期反应。在对蜱具有遗传抗性和易感性的受感染牛中测量了阳性和阴性急性期蛋白。在严重感染期间，易感牛体内的触珠蛋白水平显着增加；抗药牛血清淀粉样蛋白 A 水平升高；抗性牛的α-L-酸性糖蛋白水平显着下降；易感牛的转铁蛋白水平显着下降。 总之，蜱虫感染会引发急性期反应，并且特定急性期蛋白的增强根据宿主的遗传组成而有所不同。急性期蛋白可能构成有用的生物特征，用于监测蜱虫感染引起的应激。 (c) 2007 Elsevier Inc. 保留所有权利。
Tick bites may trigger acute phase responses. Positive and negative acute phase proteins were measured in infested cattle genetically resistant and susceptible to ticks. During heavier infestations levels of haptoglobin increased significantly in susceptible bovines; levels of serum amyloid A increased in resistant bovines; levels of alpha-l-acid glycoprotein decreased significantly in resistant bovines; levels of transferrin decreased significantly in susceptible bovines.In conclusion, tick infestations trigger acute phase responses and enhancement of specific acute phase proteins differs according to the genetic composition of hosts. Acute phase proteins may constitute useful biological signatures for monitoring the stress induced by tick infestations. (c) 2007 Elsevier Inc. All rights reserved.